I-Anticoagulation iyinqubo yokunciphisa ukwakheka kwe-fibrin thrombus ngokusebenzisa izidakamizwa ze-anticoagulant ukunciphisa inqubo ye-intrinsic pathway kanye ne-intrinsic coagulation pathway.

Umuthi we-anti-platelet ukuthatha izidakamizwa ezilwa ne-platelet ukunciphisa ukunamathela nokusebenza kokuhlanganisa kwamaplatelet, ngaleyo ndlela kuncishiswe inqubo yokwakheka kwe-platelet thrombus.Emisebenzini yomtholampilo, izidakamizwa ezivame ukusetshenziswa kakhulu ze-anticoagulant zihlanganisa i-warfarin ne-heparin, enciphisa amathuba okwakheka kwe-fibrinogen thrombus ngokusebenzisa izindlela ezahlukene ze-anticoagulant.Isibonelo, i-warfarin ivame ukusetshenziswa ekwelashweni kwe-anticoagulant ngemva kokuhlinzwa kwe-valve yenhliziyo, futhi i-heparin ivame ukusetshenziswa ekwelapheni i-thrombosis ye-venous ephansi.

Izidakamizwa ezivamile ze-antiplatelet zihlanganisa i-aspirin, i-Plavix, njll. Le mithi ingavimbela ukuhlanganiswa kweplatelet ngokusebenzisa izixhumanisi ezihlukene, ngaleyo ndlela ivimbele ukwakheka kwe-platelet thrombus.Ngokomtholampilo, isetshenziselwa ukuvimbela isifo senhliziyo, i-cerebral thrombosis nezinye izifo.