I-PT isho isikhathi se-prothrombin kwezokwelapha, futhi i-APTT isho isikhathi se-thromboplastin esicushwe ngokwengxenye kwezokwelapha.Umsebenzi wokuhlangana kwegazi womzimba womuntu ubaluleke kakhulu.Uma ukusebenza kwe-blood coagulation kungavamile, kungase kubangele i-thrombosis noma ukopha, okungase kube yingozi kakhulu impilo yesiguli.Ukuqapha komtholampilo kwamanani e-PT kanye ne-APTT kungasetshenziswa njengezinga lokusebenzisa ezinye izidakamizwa ze-anticoagulant emisebenzini yomtholampilo.Uma amanani alinganisiwe ephakeme kakhulu, kusho ukuthi umthamo wezidakamizwa ze-anticoagulant udinga ukuncishiswa, ngaphandle kwalokho ukopha kuzovela kalula.

1. Isikhathi se-Prothrombin (PT): Ingenye yezinkomba ezibucayi kakhulu zesistimu yokuhlangana kwegazi lomuntu.Kubaluleke kakhulu ukwelula isikhathi ngaphezu kwamasekhondi angu-3 ekusebenzeni komtholampilo, okungase kubonise ukuthi umsebenzi we-exogenous coagulation ujwayelekile yini.Ukwelula ngokuvamile kubonakala ekuhlanganiseni kokuzalwa kokuntuleka kwe-Factor, isifo sokuqina kwesibindi, ukwehluleka kwesibindi nezinye izifo.Ngaphezu kwalokho, ukulinganisa ngokweqile kwe-heparin ne-warfarin kungase futhi kubangele i-PT ende;

2. Isikhathi esisebenzayo se-thromboplastin (APTT): Ngokuyinhloko inkomba ebonisa umsebenzi we-endogenous blood coagulation ekusebenzeni komtholampilo.Ukwelulwa okuphawulekayo kwe-APTT kubonakala ikakhulukazi ekuntuleni kokuzalwa noma okutholiwe kwe-coagulation factor, njenge-hemophilia ne-systemic lupus erythematosus.Uma umthamo wezidakamizwa ze-anticoagulant osetshenziswa ngenxa ye-thrombosis ungajwayelekile, uzophinda ubangele ukwanda okukhulu kwe-APTT.Uma inani elilinganisiwe liphansi, cabanga ukuthi isiguli sisesimweni sokuqina kwe-hypercoagulable, njenge-deep vein thrombosis.

Uma ufuna ukwazi ukuthi i-PT yakho ne-APTT zijwayelekile yini, udinga ukucacisa ububanzi bazo obujwayelekile.Ububanzi obujwayelekile be-PT yimizuzwana engu-11-14, kanti ububanzi obujwayelekile be-APTT ngamasekhondi angu-27-45.Ukwelulwa kwe-PT okungaphezu kwamasekhondi angu-3 kunokubaluleka okukhulu komtholampilo, futhi ukunwetshwa kwe-APTT kwamasekhondi angaphezu kwe-10 kunokubaluleka okuqinile komtholampilo.