I-Thrombosis ngokuvamile ibangelwa ukulimala kwamangqamuzana e-cardiovascular endothelial, isimo esingavamile sokugeleza kwegazi, kanye nokukhuphuka kwegazi.

1. Ukulimala kwengqamuzana le-cardiovascular endothelial cell: Ukulimala kwe-vascular endothelial cell kuyimbangela ebaluleke kakhulu futhi evamile yokwakheka kwe-thrombus, evame kakhulu endocarditis ye-rheumatic ne-infective, i-atherosclerotic plaque ulcer eqinile, ukunyakaza okubuhlungu noma okuvuthayo Indawo yokulimala kwe-venous, njll. Ngaphezu kwalokho, ngemuva kwe-hypoxia, ukushaqeka, i-sepsis kanye ne-endotoxin yebhaktheriya kubangela ukulimala okukhulu kwe-endothelial kuwo wonke umzimba, i-collagen engaphansi kwe-endothelium ivuselela inqubo ye-coagulation, okuholela ekusakazeni kwe-intravascular coagulation, kanye namafomu e-thrombus ku-microcirculation yomzimba wonke.

2. Isimo esingavamile sokugeleza kwegazi: ikakhulukazi kubhekiselwa ekuncipheni kokugeleza kwegazi kanye nokukhiqizwa kwama-eddies ekugelezeni kwegazi, njll. Izinto ezicushiwe zokuxinana kanye ne-thrombin zifinyelela ekugxiliseni okudingwa ukujiya endaweni, okulungele ukuhlangana kwegazi. ukwakheka kwe-thrombus.Phakathi kwabo, i-veins ijwayele kakhulu i-thrombus, evame kakhulu ezigulini ezinesifo senhliziyo, ukugula okungapheli kanye nokuphumula kombhede ngemuva kokuhlinzwa.Ngaphezu kwalokho, ukugeleza kwegazi enhliziyweni nasemithanjeni kuyashesha, futhi akulula ukwenza i-thrombus.Kodwa-ke, lapho ukugeleza kwegazi ku-atrium yangakwesobunxele, i-aneurysm, noma igatsha lomkhumbi wegazi kuhamba kancane futhi i-eddy current yenzeka ngesikhathi se-mitral valve stenosis, iphinde ibe sengozini ye-thrombosis.

3. Ukwanda kwe-blood coagulation: Ngokuvamile, ukwanda kwamaplatelet kanye nezici zokuxhuma egazini, noma ukwehla komsebenzi wesistimu ye-fibrinolytic, kuholela esimweni se-hypercoagulable egazini, esivame kakhulu ezimweni ze-hypercoagulable zofuzo futhi ezitholwe.

Ukwengeza, ukubuya kwegazi le-venous elibi nakho kungabangela.Ngokusho kokuxilongwa ngempumelelo kwesifo somuntu siqu, ukuvinjelwa kwesayensi okuhlosiwe kanye nokwelashwa kungafinyelelwa ukusiza ukululama kwezempilo.