I-APTT imele isikhathi se-thromboplastin esinqunyiwe esisebenzayo, esibhekisela esikhathini esidingekayo ukuze kwengezwe ingxenye ye-thromboplastin ku-plasma ehloliwe futhi kubhekwe isikhathi esidingekayo sokuhlangana kwe-plasma.I-APTT iwukuhlolwa kokuhlola okubucayi futhi okuvame ukusetshenziswa kakhulu ukuze kutholwe isistimu ye-endogenous coagulation.Ibanga elijwayelekile lingamasekhondi angu-31-43, kanti imizuzwana engu-10 ngaphezu kokulawula okuvamile linokubaluleka komtholampilo.Ngenxa yomehluko phakathi kwabantu ngabanye, uma izinga lokufinyezwa kwe-APTT lilincane kakhulu, kungase futhi kube yinto evamile, futhi asikho isidingo sokwethuka ngokweqile, nokuhlola kabusha okuvamile kwanele.Uma uzizwa ungaphilile, bonana nodokotela kusenesikhathi.

Ukufinyezwa kwe-APTT kubonisa ukuthi igazi lisesimeni se-hypercoagulable, esivamile ezifweni ze-cardiovascular and cerebrovascular thrombotic, njenge-cerebral thrombosis nesifo senhliziyo.

1. I-Cerebral thrombosis

Iziguli ezine-APTT efushanisiwe kakhulu kungenzeka zibe ne-cerebral thrombosis, evame kakhulu ezifweni ezihlobene ne-hypercoagulation yegazi ebangelwa izinguquko ezingxenyeni zegazi, njenge-hyperlipidemia.Ngalesi sikhathi, uma izinga le-cerebral thrombosis lilincane uma kuqhathaniswa, kuzovela kuphela izimpawu zokungatholakali kwegazi okwanele ebuchosheni, njengesiyezi, ikhanda elibuhlungu, isicanucanu, nokuhlanza.Uma izinga le-cerebral thrombosis linzima ngokwanele ukuthi libangele i-cerebral parenchymal ischemia enzima, izimpawu zomtholampilo ezifana nokungasebenzi kahle kwezitho zomzimba, ukukhubazeka kwenkulumo, nokungakwazi ukuzithiba.Ezigulini ezine-acute cerebral thrombosis, ukuhogela umoya-mpilo kanye nokusekelwa komoya-mpilo kuvame ukusetshenziselwa ukwandisa ukutholakala komoyampilo.Lapho izimpawu zesiguli zisongela ukuphila, i-thrombolysis esebenzayo noma ukuhlinzwa kokungenelela kufanele kwenziwe ukuze kuvulwe imithambo yegazi ngokushesha ngangokunokwenzeka.Ngemuva kokuthi izimpawu ezibucayi ze-cerebral thrombosis zincishisiwe futhi zilawulwe, isiguli kufanele sisabambelele emikhubeni emihle yokuphila futhi sithathe imithi yesikhathi eside ngaphansi kokuqondisa kodokotela.Kunconywa ukuthi udle ukudla okunosawoti omncane kanye namafutha aphansi ngesikhathi sokululama, udle imifino nezithelo eziningi, ugweme ukudla ukudla okune-sodium ephezulu njenge-bacon, ukhukhamba, ukudla okusemathinini, njll, futhi ugweme ukubhema notshwala.Zivocavoce ngokusesilinganisweni uma isimo sakho somzimba sikuvumela.

2. Isifo senhliziyo

Ukufinyezwa kwe-APTT kubonisa ukuthi isiguli singase sibe nesifo senhliziyo, esivame ukubangelwa yi-coronary hypercoagulation eholela ku-stenosis noma ukuvinjelwa kwe-lumen yomkhumbi, okuholela ekuhambisaneni kwe-ischemia ye-myocardial, i-hypoxia, ne-necrosis.Uma izinga lokuvinjelwa komthambo we-coronary liphakeme ngokuqhathaniswa, isiguli singase singabi nazo izimpawu zomtholampilo ezisobala esimweni sokuphumula, noma singase sibe nokungakhululeki okufana nokucinana kwesifuba nobuhlungu besifuba ngemva kwemisebenzi.Uma izinga lokuvinjelwa komthambo we-coronary linzima, ingozi ye-myocardial infarction iyanda.Iziguli zingase zizwe ubuhlungu besifuba, isifuba esiqinile, kanye nokuphefumula lapho ziphumule noma zijabule ngokomzwelo.Ubuhlungu bungase budlulele kwezinye izingxenye zomzimba futhi buqhubeke ngaphandle kokukhululeka.Ezigulini eziqala kakhulu isifo senhliziyo, ngemva kokuphathwa kwe-nitroglycerin noma i-isosorbide dinitrate ngaphansi kolimi, bonana nodokotela ngokushesha, futhi udokotela uhlola ukuthi ingabe i-coronary stent implantation noma i-thrombolysis iyadingeka ngokushesha.Ngemuva kwesigaba esibucayi, ukwelashwa kwe-antiplatelet yesikhathi eside kanye ne-anticoagulant kuyadingeka.Ngemva kokukhishwa esibhedlela, isiguli kufanele sidle ukudla okunosawoti omncane nokunamafutha amancane, siyeke ukubhema nokuphuza, sivivinye umzimba ngendlela efanele, futhi sinake ukuphumula.