Izimbangela ze-thrombosis zingaba kanje:

1. Kungase kuhlotshaniswe nokulimala kwe-endothelial, futhi i-thrombus yakheka ku-endothelium ye-vascular.Ngokuvamile ngenxa yezizathu ezihlukahlukene ze-endothelium, njengamakhemikhali noma izidakamizwa noma i-endotoxin, noma ukulimala kwe-endothelial okubangelwa i-atheromatous plaque, njll, amafomu e-endothelial thrombus ngemva kokulimala;

2. Isibonelo, ukuhlangana kwegazi, ukwanda komsebenzi we-platelet, noma ukungahambi kahle kwe-blood coagulation mechanism nakho kungaholela ekwakhekeni kwe-thrombus;

3. Izinga lokugeleza kwegazi liyancipha noma umthamo wegazi uyancipha, futhi ukuhlushwa kwegazi kuyanda, okungase kuholele ekwakhiweni kwe-thrombus, ngakho-ke kunezizathu eziningi zokubunjwa kwe-thrombus;

4. Ngaphandle kwezizathu ezibalulwe ngenhla, izimbangela ze-thrombus nazo zihlanganisa umsebenzi owandisiwe wesistimu ye-fibrinolytic.Ngaphezu kwalokho, kukhona ukwanda kwenani lamaplatelet, okungase kubangele isifo se-thrombotic, ngakho-ke kusenezizathu eziningi.