I-coagulopathy ngokuvamile ibhekisela esifweni sokungasebenzi kahle kwe-coagulation, esibangelwa izici ezihlukahlukene eziholela ekuntulekeni kwezinto ezihlangene noma ukungasebenzi kahle kwe-coagulation, okuholela ochungechungeni lokopha noma ukopha.Ingahlukaniswa ngezifo ezibangelwa yi-congenital and hereditary coagulation dysfunction, ezitholwe yizinkinga ze-coagulation ezitholakalayo.

1. Ukuphazamiseka kokuzala kofuzo: ngenxa yezici zokuzalwa ezifana nokukhubazeka kwezakhi zofuzo, ngokuvamile i-chromosome engu-X ithwala ifa eliphindaphindayo, okuvamile i-hemophilia, ukubonakaliswa kwemitholampilo kuwukopha okuzenzakalelayo, i-hematoma, i-dysphagia, njll. Ngokuhlolwa kwelabhorethri, kungatholwa ukuthi isiguli i-thromboplastin ikhiqizwa kabi, futhi ngaphansi kokuqondisa kukadokotela, i-vitamin K1, amaphilisi e-phensulfame nezinye izidakamizwa zingafakwa ukuze kuthuthukiswe ukuhlangana kwegazi;

2. Isifo sokungasebenzi kahle kwe-coagulation: sisho ukungasebenzi kahle kwe-coagulation okubangelwa izidakamizwa, izifo noma ubuthi, njll. Okuvame kakhulu ukungasebenzi kahle kwe-coagulation okubangelwa ukushoda kwe-vitamin K nesifo sesibindi.Kuyadingeka ukwelapha ngenkuthalo izici eziyinhloko ngokusho kweseluleko sikadokotela.Uma kubangelwa izidakamizwa, umuthi kufanele uncishiswe noma umiswe ngokufanelekile, bese kungezwa izici zokuhlangana kwegazi ezifana ne-vitamin K ngokwesimo sokopha, kanye nokumpontshelwa kwe-plasma nakho kungasetshenziswa.Uma i-thrombus ibangelwa ukungasebenzi kahle kwe-coagulation, ukwelashwa kwe-anticoagulant, njenge-heparin sodium nezinye izidakamizwa ze-anticoagulant, kuyadingeka.