Isizathu se-thrombosis sihlanganisa i-lipids ephezulu yegazi, kodwa akuwona wonke amahlule egazi abangelwa ama-lipids aphezulu egazi.Okusho ukuthi, imbangela ye-thrombosis akuyona yonke into ngenxa yokuqoqwa kwezinto ze-lipid kanye ne-viscosity ephezulu yegazi.Esinye isici esiyingozi ukunqwabelana ngokweqile kwamaplatelet, amangqamuzana egazi ajiyisa igazi.Ngakho-ke uma sifuna ukuqonda ukuthi i-thrombus yakheka kanjani, sidinga ukuqonda ukuthi kungani amaplatelet ehlangana?
Ngokuvamile, umsebenzi oyinhloko wama-platelet ukuhlangana.Lapho isikhumba sethu sihlukumezekile, kungase kube nokopha ngalesi sikhathi.Isignali yokopha izodluliselwa ohlelweni oluphakathi.Ngalesi sikhathi, ama-platelet azobuthana endaweni yenxeba futhi aqhubeke enqwabelana esilondeni, ngaleyo ndlela avimbele ama-capillaries futhi afeze injongo ye-hemostasis.Ngemva kokulimala, kungase kwakheke utwayi lwegazi enxebeni, empeleni elakheka ngemva kokuhlanganiswa kweplatelet.
Uma isimo esingenhla senzeka emithanjeni yethu yegazi, kuvame kakhulu ukuthi imithambo yegazi ye-arterial ilimele.Ngalesi sikhathi, ama-platelet azohlangana endaweni eyonakele ukuze afeze injongo ye-hemostasis.Ngalesi sikhathi, umkhiqizo we-platelet aggregation awuwona uqweqwe lwegazi, kodwa i-thrombus esikhuluma ngayo namuhla.Ngakho ingabe i-thrombosis emithanjeni yegazi yonke ibangelwa ukulimala komkhumbi wegazi?Ngokuvamile, i-thrombus yakhiwe ngempela ngokuphuka komkhumbi wegazi, kodwa akuyona indaba yokuphuka komkhumbi wegazi, kodwa ukulimala kodonga lwangaphakathi lomkhumbi wegazi.
Ema-atherosclerotic plaques, uma ukuphuka kwenzeka, amafutha afakwe ngalesi sikhathi angase abonakale egazini.Ngale ndlela, ama-platelet egazini ayakhangwa.Ngemva kokuba ama-platelet ethola isignali, azoqhubeka ehlanganisa lapha futhi ekugcineni enze i-thrombus.
Ukukubeka kalula, i-lipids ephezulu yegazi ayiyona imbangela eqondile ye-thrombosis.I-Hyperlipidemia iwukuthi kukhona ama-lipids amaningi emithanjeni yegazi, futhi ama-lipids awahlangani abe amaqoqo emithanjeni yegazi.Kodwa-ke, uma izinga le-lipid egazini liqhubeka nokukhuphuka, maningi amathuba okuthi kuvele i-atherosclerosis ne-plaque.Ngemuva kokuthi lezi zinkinga zenzeke, kungase kube khona ukuphuka, futhi i-thrombus kulula ukwenza ngalesi sikhathi.
Ikhadi lebhizinisi
I-Chinese WeChat
IsiNgisi WeChat