Kunezinhlelo ze-coagulation kanye ne-anticoagulation egazini lomuntu.Ngaphansi kwezimo ezijwayelekile, lezi ezimbili zigcina ibhalansi eguquguqukayo ukuze kuqinisekiswe ukugeleza kwegazi okuvamile emithanjeni yegazi, futhi ngeke kwakha i-thrombus.Endabeni yomfutho wegazi ophansi, ukuntuleka kwamanzi okuphuza, njll., ukugeleza kwegazi kuzohamba kancane, igazi lizogxila futhi libukeke, umsebenzi we-coagulation uzoba hyperactive noma umsebenzi we-anticoagulation uzoba buthakathaka, okuzophula le bhalansi. futhi wenze abantu "be-thrombotic state".I-Thrombosis ingenzeka noma kuphi emithanjeni yegazi.I-thrombus igeleza negazi emithanjeni yegazi.Uma ihlala emithanjeni yobuchopho futhi ivimbe ukugeleza kwegazi okuvamile emithanjeni yobuchopho, i-cerebral thrombosis, ezokwenza i-ischemic stroke.Imithambo yenhliziyo ingenza i-myocardial infarction, ngaphezu kwalokho, i-arterial thrombosis emaphethelweni aphansi, i-thrombosis ejulile ye-venous, kanye ne-pulmonary embolism.

I-Thrombosis, iningi labo liyoba nezimpawu ezimbi kakhulu ekuqaleni, njenge-hemiplegia ne-aphasia ngenxa ye-cerebral infarction;i-colic eyingozi kakhulu ye-myocardial infarction;ubuhlungu obukhulu besifuba, i-dyspnea, i-hemoptysis ebangelwa i-infarction yamaphaphu;Kungabangela ubuhlungu emilenzeni, noma umuzwa obandayo kanye ne-claudication ephakathi.Inhliziyo ebucayi kakhulu, i-cerebral infarction kanye ne-pulmonary infarction nakho kungabangela ukufa kungazelelwe.Kodwa ngezinye izikhathi azikho izimpawu ezicacile, njenge-thrombosis evamile ye-vein ejulile yomkhawulo ophansi, ithole kuphela elibuhlungu futhi lingakhululekile.Iziguli eziningi zicabanga ukuthi kungenxa yokukhathala noma ukubanda, kodwa azikuthathi ngokungathi sína, ngakho kulula ukuphuthelwa isikhathi esingcono kakhulu sokwelashwa.Kuyadabukisa ikakhulukazi ukuthi odokotela abaningi bathambekele ekuxilongeni ngokungeyikho.Uma kwenzeka i-edema yomkhawulo ophansi, ngeke nje ilethe ubunzima ekwelapheni, kodwa futhi ishiya kalula i-sequelae.