I-D-Dimer njengenkomba yokubikezela izifo ezihlukahlukene:

Ngenxa yobudlelwano obuseduze phakathi kwesistimu ye-coagulation nokuvuvukala, ukulimala kwe-endothelial, nezinye izifo ezingezona ze-thrombotic ezifana nokutheleleka, ukuhlinzwa noma ukuhlukumezeka, ukwehluleka kwenhliziyo, nezimila ezimbi, ukwanda kwe-D-Dimer kuvame ukubonwa.Ocwaningweni, kutholwe ukuthi ukubikezela okubi okuvame kakhulu kwalezi zifo kuseyi-thrombosis, i-DIC, njll. Iningi lalezi zinkinga ziyizifo ezivame kakhulu ezihlobene noma izifunda ezibangela ukuphakama kwe-D-Dimer.Ngakho-ke i-D-Dimer ingasetshenziswa njengenkomba yokuhlola ebanzi futhi ebucayi yezifo.

I-1.Ezigulini ezinomdlavuza, ucwaningo oluningi luye lwathola ukuthi izinga lokusinda leminyaka engu-1-3 yeziguli ezinomdlavuza ezine-D-Dimer ephakeme liphansi kakhulu kunalabo abane-D-Dimer evamile.I-D-Dimer ingasetshenziswa njengenkomba yokuhlola ukubikezelwa kweziguli ezibulalayo zesimila.

I-2.Ezigulini ze-VTE, izifundo eziningi ziye zaqinisekisa ukuthi iziguli ezine-D-Dimer ezinhle ngesikhathi se-anticoagulation zinengozi ephakeme ye-2-3 yokuphindaphinda kwe-thrombotic elandelayo uma kuqhathaniswa neziguli ezingezinhle.Okunye ukuhlaziywa kwe-meta kwabahlanganyeli be-1818 ezifundweni ze-7 kubonise ukuthi i-D-Dimer engavamile ingenye yezibikezelo eziyinhloko zokuphindaphinda kwe-thrombotic ezigulini ze-VTE, futhi i-D-Dimer ifakwe kumamodeli amaningi okubikezela ingozi yokuphindaphinda kwe-VTE.

3.Ezigulini ezishintsha i-valve ngomshini (MHVR), ucwaningo lokulandelela lwesikhathi eside lwabahlanganyeli abangu-618 lubonise ukuthi iziguli ezinamazinga angavamile e-D-Dimer phakathi nesikhathi se-warfarin ngemva kwe-MHVR zazisengozini yezehlakalo ezimbi cishe izikhathi ezi-5 ngaphezu kwalezo. namazinga ajwayelekile.Ukuhlaziywa kokuhlanganiswa kwe-Multivariate kuqinisekisile ukuthi amazinga e-D-Dimer ayezibikezelo ezizimele ze-thrombosis noma izenzakalo zenhliziyo phakathi ne-anticoagulation.

I-4.Kuziguli ezine-atrial fibrillation (AF), i-D-Dimer ingabikezela izenzakalo ze-thrombotic kanye ne-cardiovascular ngesikhathi se-anticoagulation yomlomo.Ucwaningo olulindelekile lweziguli ezingama-269 ezine-atrial fibrillation olwalandelwa cishe iminyaka emi-2 lubonise ukuthi ngesikhathi sokunqanda ukuqunjelwa ngomlomo, cishe ama-23% eziguli ezahlangabezana nezinga le-INR zabonisa amazinga e-D-Dimer angejwayelekile, kuyilapho iziguli ezinamaleveli e-D-Dimer angejwayelekile zine-15.8 futhi Izikhathi ezingu-7.64 ingozi ephakeme ye-thrombotic kanye nezenzakalo zenhliziyo ezihambisanayo uma kuqhathaniswa neziguli ezinamazinga ajwayelekile e-D-Dimer, ngokulandelana.
Kulezi zifo ezithile noma iziguli, i-D-Dimer ephakeme noma eqhubekayo ivame ukukhombisa ukubikezela okungekuhle noma ukuwohloka kwesimo.