I-coronavirus pneumonia ka-2019 (COVID-19) isisabalele emhlabeni jikelele.Ucwaningo lwangaphambilini lukhombisile ukuthi ukutheleleka nge-coronavirus kungaholela ekuphazamisekeni kwe-coagulation, okubonakaliswa ikakhulukazi njengesikhathi eside se-thromboplastin esisebenza isikhathi eside (APTT), i-thrombocytopenia, i-D-dimer (DD) Amazinga aphezulu kanye nokusatshalaliswa kwe-intravascular coagulation (DIC), okuhlotshaniswa nokufa okuphezulu.
Ukuhlaziywa kwakamuva kwe-meta-coagulation ezigulini ezine-COVID-19 (okubandakanya izifundo eziyi-9 zokubheka emuva ezinenani leziguli eziyi-1 105) kubonise ukuthi uma kuqhathaniswa neziguli ezithambile, iziguli ezinzima ze-COVID-19 zazinamanani aphezulu kakhulu e-DD, isikhathi se-Prothrombin (PT) yayiyinde;ukwanda kwe-DD kwakuyisici engcupheni yokwanda kanye sengozini yokufa.Kodwa-ke, ukuhlaziywa kwe-Meta okukhulunywe ngenhla kufaka phakathi izifundo ezimbalwa futhi kufaka phakathi izifundo ezimbalwa zocwaningo.Muva nje, kushicilelwe izifundo ezinkulu zemitholampilo ezimayelana nokusebenza kwe-coagulation ezigulini ezine-COVID-19, futhi izici zokuhlangana kweziguli ezine-COVID-19 ezibikwe ezifundweni ezahlukahlukene nazo Akunjalo impela.
Ucwaningo lwakamuva olusekelwe kudatha kazwelonke lubonise ukuthi ama-40% eziguli ze-COVID-19 zisengozini enkulu ye-venous thromboembolism (VTE), kanti u-11% weziguli ezisengozini enkulu zikhula ngaphandle kwezinyathelo zokuvimbela.I-VTE.Imiphumela yolunye ucwaningo iphinde yakhombisa ukuthi ama-25% eziguli ezinzima ze-COVID-19 zakha i-VTE, kanti izinga lokushona kweziguli ezine-VTE laliphezulu kakhulu lafinyelela ku-40%.Kukhombisa ukuthi iziguli ezine-COVID-19, ikakhulukazi iziguli ezinzima noma ezigula kakhulu, zisengozini enkulu ye-VTE.Isizathu esingenzeka ukuthi iziguli ezigula kakhulu nezigula kakhulu zinezifo eziningi ezingaphansi, njengomlando we-cerebral infarction kanye nesimila esiyingozi, okuyizinto zonke ezibeka engcupheni ye-VTE, futhi iziguli ezinzima nezigula kakhulu zilala embhedeni isikhathi eside, zihlezi, zingakwazi ukuhamba. , futhi ibekwe kumadivayisi ahlukahlukene.Izinyathelo zokwelapha ezifana namashubhu nazo ziyizici eziyingozi ze-thrombosis.Ngakho-ke, ezigulini ezigula kakhulu futhi ezigula kakhulu ze-COVID-19, kungenziwa ukuvinjelwa kwemishini kwe-VTE, okufana namasokisi anwebekayo, iphampu ye-inflatable, njll., kungenziwa;ngesikhathi esifanayo, umlando wezokwelapha odlule wesiguli kufanele uqondwe ngokugcwele, futhi umsebenzi we-coagulation wesiguli kufanele uhlolwe ngesikhathi esifanele.ezigulini, i-prophylactic anticoagulation ingaqalwa uma kungekho ukuphikisana
Imiphumela yamanje iphakamisa ukuthi ukuphazamiseka kwe-coagulation kuvame kakhulu ezigulini ezinzima, ezigula kakhulu, kanye neziguli ezifayo ze-COVID-19.Ukubalwa kweplatelet, amanani e-DD kanye ne-PT ahlotshaniswa nokuqina kwesifo futhi angasetshenziswa njengezinkomba eziyisixwayiso zangaphambi kwesikhathi zokuwohloka kwezifo ngesikhathi sokulaliswa esibhedlela.