I-blood coagulation ngokuvamile ayikho ukuthi kuhle noma kubi.Ukujiya kwegazi kunebanga lesikhathi elijwayelekile.Uma ishesha kakhulu noma ihamba kancane, izoba yingozi emzimbeni womuntu.

I-blood coagulation izoba phakathi kwebanga elithile elijwayelekile, ukuze ingabangeli ukuphuma kwegazi nokwakheka kwe-thrombus emzimbeni womuntu.Uma i-coagulation yegazi ishesha kakhulu, ngokuvamile kubonisa ukuthi umzimba womuntu usesimweni se-hypercoagulable, futhi izifo zenhliziyo ne-cerebrovascular zivame ukwenzeka, njenge-cerebral infarction kanye ne-Myocardial infarction, i-thrombosis ye-venous ephansi kanye nezinye izifo.Uma igazi lesiguli lijiya kancane kakhulu, kungenzeka libe nokungasebenzi kahle kwe-coagulation, othambekele ekubeni nezifo ezophayo, njenge-hemophilia, futhi ezimweni ezimbi kakhulu, lizoshiya ukukhubazeka kwamalunga nokunye ukusabela okungekuhle.

Umsebenzi omuhle we-thrombin ubonisa ukuthi ama-platelet asebenza kahle futhi anempilo kakhulu.I-coagulation isho inqubo yegazi eliguqukayo lisuka esimweni esigelezayo liye esimweni sejeli, futhi ingqikithi yalo inqubo yokuguqula i-fibrinogen encibilikayo ibe yi-fibrinogen e-plasma engasebenzi.Ngomqondo omncane, lapho imithambo yegazi ilimele, umzimba ukhiqiza izici zokuhlangana, ezicushwayo ukuze zikhiqize i-thrombin, egcina iguqule i-fibrinogen ibe i-fibrin, ngaleyo ndlela ikhuthaze ukuhlangana kwegazi.I-coagulation ngokuvamile ihlanganisa nomsebenzi we-platelet.

Ukwahlulela ukuthi i-coagulation yinhle noma cha, ikakhulukazi ngokopha nokuhlolwa kwaselabhorethri.Ukungasebenzi kahle kwe-coagulation kubhekisela ezinkingeni ezinezici zokujiya, ukuncipha kwenani noma ukusebenza okungavamile, kanye nochungechunge lwezimpawu zokopha.Kungase kuvele ukopha, futhi i-purpura, i-ecchymosis, i-epistaxis, izinsini ezophayo, ne-hematuria kungabonakala esikhumbeni nasolwelwesini lwamafinyila.Ngemva kokulimala noma ukuhlinzwa, inani lokopha liyakhula futhi isikhathi sokopha singanwetshwa.Ngokutholwa kwesikhathi se-prothrombin, isikhathi se-prothrombin esicushwe kancane nezinye izinto, kutholakala ukuthi umsebenzi wokuhlangana awumuhle, futhi imbangela yokuxilongwa kufanele icaciswe.