Yiziphi Ama-Anticoagulants Egazi?

Ama-reagents amakhemikhali noma izinto ezingavimbela ukuhlangana kwegazi zibizwa ngokuthi ama-anticoagulants, njengama-anticoagulants emvelo (i-heparin, i-hirudin, njll.), I-Ca2 + chelating agents (i-sodium citrate, i-potassium fluoride).Ama-anticoagulant asetshenziswa kakhulu ahlanganisa i-heparin, i-ethylenediaminetetraacetate (usawoti we-EDTA), i-citrate, i-oxalate, njll. Ekusetshenzisweni okungokoqobo, ama-anticoagulant kufanele akhethwe ngokuvumelana nezidingo ezahlukene ukuze kutholwe imiphumela emihle.

Umjovo weHeparin

Umjovo we-Heparin yi-anticoagulant.Isetshenziselwa ukunciphisa amandla egazi okujiyisa futhi isize ekuvimbeleni amahlule ayingozi ukuthi akheke emithanjeni yegazi.Lesi sidakamizwa ngezinye izikhathi sibizwa ngokuthi i-blood thinner, nakuba empeleni singalinciphisi igazi.I-Heparin ayiwaqedi amahlule egazi asevele akhekile, kodwa ingawavimbela ukuba abe mkhulu, okungaholela ezinkingeni ezinkulu kakhulu.

I-Heparin isetshenziselwa ukuvimbela noma ukwelapha izifo ezithile ze-vascular, inhliziyo namaphaphu.I-Heparin iphinde isetshenziselwe ukuvimbela ukujiya kwegazi ngesikhathi sokuhlinzwa kwenhliziyo evulekile, ukuhlinzwa kwenhliziyo, ukukhishwa kwezinso kanye nokumpontshelwa igazi.Isetshenziswa ngemithamo ephansi ukuvikela i-thrombosis kwezinye iziguli, ikakhulukazi lezo okufanele zihlinzwe izinhlobo ezithile noma okufanele zihlale embhedeni isikhathi eside.I-Heparin ingabuye isetshenziselwe ukuxilonga nokwelapha isifo esibi segazi esibizwa ngokuthi i-dissemination intravascular coagulation.

Ingathengwa kuphela ngencwadi kadokotela.

EDTC Usawoti

Ikhemikhali elihlanganisa ama-ion ensimbi athile, njenge-calcium, i-magnesium, umthofu, nensimbi.Isetshenziselwa ukwelapha ukuvimbela amasampula egazi ukuthi ahlule futhi akhiphe i-calcium nomthofu emzimbeni.Ibuye isetshenziselwe ukuvimbela amagciwane ukuthi enze ama-biofilms (izingqimba ezincanyana ezinamathiselwe phezulu).Kuyi-ejenti ye-chelating.Ebizwa nangokuthi i-ethylene diacetic acid kanye ne-ethylene diethylenediamine tetraacetic acid.

I-EDTA-K2 enconywe i-International Hematology Standardization Committee inokuncibilika okuphezulu kakhulu kanye nesivinini esisheshayo sokunqanda ukuphuma kwegazi.