1. I-Plasma D-dimer assay iyisivivinyo sokuqonda umsebenzi wesibili we-fibrinolytic.

Umgomo wokuhlola: I-Anti-DD i-monoclonal antibody ifakwe ezinhlayiyeni ze-latex.Uma kukhona i-D-dimer ku-plasma ye-receptor, ukusabela kwe-antigen-antibody kuzokwenzeka, futhi izinhlayiya ze-latex zizohlangana.Kodwa-ke, lokhu kuhlolwa kungaba kuhle kunoma yikuphi ukopha ngokukwakheka kwehlule legazi, ngakho kunokucaciswa okuphansi nokuzwela okuphezulu.

2. Kunemithombo emibili ye-D-dimer ku-vivo

(1) Isimo se-hypercoagulable kanye ne-hyperfibrinolysis yesibili;

(2) i-thrombolysis;

I-D-dimer ikhombisa ikakhulukazi umsebenzi we-fibrinolytic.Ukwanda noma okuhle kubonakala ku-hyperfibrinolysis yesibili, njenge-hypercoagulable state, ukusatshalaliswa kwe-intravascular coagulation, isifo sezinso, ukwenqatshwa kokufakelwa kwesitho, ukwelashwa kwe-thrombolytic, njll.

3. Uma nje kukhona i-thrombosis esebenzayo kanye nomsebenzi we-fibrinolytic emithanjeni yegazi yomzimba, i-D-dimer izokhula.

Isibonelo: i-myocardial infarction, i-cerebral infarction, i-pulmonary embolism, i-venous thrombosis, ukuhlinzwa, isimila, ukusatshalaliswa kwe-intravascular coagulation, ukutheleleka kanye ne-necrosis yezicubu kungaholela ekwandeni kwe-D-dimer.Ikakhulukazi kubantu asebekhulile kanye neziguli ezisesibhedlela, ngenxa ye-bacteremia nezinye izifo, kulula ukubangela ukuhlangana kwegazi okungavamile futhi kubangele ukwanda kwe-D-dimer.

4. Ukucaciswa okuboniswa yi-D-dimer akubhekiseli ekusebenzeni kwesifo esithile esithile, kodwa kuzici ezivamile ze-pathological zaleli qembu elikhulu lezifo ezine-coagulation kanye ne-fibrinolysis.

Ngokwethiyori, ukwakheka kwe-fibrin exhumene nesiphambano kuyi-thrombosis.Kodwa-ke, kunezifo eziningi zemitholampilo ezingase zenze uhlelo lwe-coagulation lusebenze ngesikhathi sokuvela nokuthuthukiswa kwalesi sifo.Uma i-fibrin exhunywe ngokuphambana ikhiqizwa, uhlelo lwe-fibrinolytic luzosebenza futhi i-fibrin exhunywe ngokuphambana izokwenziwa i-hydrolyzed ukuvimbela "ukuqoqwa" kwayo okukhulu.(i-thrombus ebalulekile emtholampilo), okuholela ekuphakameni okuphawulekayo kwe-D-dimer.Ngakho-ke, i-D-dimer ephakeme ayiyona i-thrombosis ebalulekile emtholampilo.Kwezinye izifo noma abantu ngabanye, kungase kube inqubo ye-pathological.