Isikhathi se-Prothrombin (PT) sibhekisela esikhathini esidingekayo ukuze i-plasma coagulation ngemva kokuguqulwa kwe-prothrombin ibe i-thrombin ngemva kokwengeza okweqile kwe-thromboplastin yethishu kanye nenani elifanele lama-ion e-calcium ku-plasma engenayo iplatelet.Isikhathi esiphezulu se-prothrombin (PT), okungukuthi, ukunwetshwa kwesikhathi, kungase kubangelwe izizathu ezihlukahlukene ezifana nezici zokuzalwa ezingavamile ze-coagulation, izici ezingavamile zokuhlangana, isimo esingavamile se-anticoagulation yegazi, njll. Ukuhlaziywa okuyinhloko kanje:

1. Izici ze-congenital coagulation ezingavamile: Ukukhiqizwa okungavamile kwanoma iyiphi into eyodwa ye-coagulation I, II, V, VII, no-X emzimbeni kuzoholela esikhathini se-prothrombin eside (PT).Iziguli zingakwazi ukwengeza izici ze-coagulation ngaphansi kokuqondisa kodokotela ukuthuthukisa lesi simo;

2. Izici ze-coagulation ezitholwe ngendlela engavamile: isifo esibi esivamile sesibindi, ukuntuleka kwe-vitamin K, i-hyperfibrinolysis, i-coagulation ye-intravascular coagulation esakazwayo, njll., lezi zici zizoholela ekuntulekeni kwezici ze-coagulation ezigulini, okuholela ekutheni isikhathi eside se-prothrombin (PT).Izimbangela eziqondile zidinga ukuhlonzwa ukuze uthole ukwelashwa okuhlosiwe.Isibonelo, iziguli ezinokuntuleka kwe-vitamin K zingelashwa nge-intravenous vitamin K1 supplementation ukuze kukhuthazwe ukubuya kwesikhathi se-prothrombin kokujwayelekile;

3. Isimo esingavamile se-anticoagulation yegazi: kunezinto ze-anticoagulant egazini noma isiguli sisebenzisa izidakamizwa ze-anticoagulant, njenge-aspirin nezinye izidakamizwa, ezinemiphumela ye-anticoagulant, ezothinta indlela yokugaya futhi andise isikhathi se-prothrombin (PT).Kunconywa ukuthi iziguli ziyeke izidakamizwa ze-anticoagulant ngaphansi kokuqondisa kodokotela futhi zishintshele kwezinye izindlela zokwelapha.

Isikhathi se-Prothrombin (PT) esinwetshwe ngaphezu kwamasekhondi angu-3 sinokubaluleka komtholampilo.Uma iphezulu kakhulu futhi ingeqi inani elivamile lamasekhondi angu-3, ​​ingabhekwa eduze, futhi ukwelashwa okukhethekile ngokuvamile akudingeki.Uma isikhathi se-prothrombin (PT) sinwetshwa isikhathi eside kakhulu, kuyadingeka ukuqhubeka nokuthola imbangela ethile futhi kwenziwe ukwelashwa okuhlosiwe.