FIB jẹ abbreviation English fun fibrinogen, ati fibrinogen jẹ ifosiwewe coagulation.A ga ẹjẹ coagulation FIB iye tumo si wipe ẹjẹ wa ni a hypercoagulable ipinle, ati thrombus ti wa ni awọn iṣọrọ akoso.
Lẹhin ti siseto coagulation eniyan ti ṣiṣẹ, fibrinogen di fibrin monomer labẹ iṣẹ ti thrombin, ati monomer fibrin le ṣajọpọ sinu polima fibrin, eyiti o ṣe iranlọwọ fun dida didi ẹjẹ ati ṣe ipa pataki ninu ilana iṣọn-ọkan.
Fibrinogen jẹ iṣelọpọ nipataki nipasẹ awọn hepatocytes ati pe o jẹ amuaradagba pẹlu iṣẹ coagulation.Iwọn deede rẹ wa laarin 2 ~ 4qL.Fibrinogen jẹ nkan ti o ni ibatan coagulation, ati pe ilosoke rẹ nigbagbogbo jẹ iṣesi ti ara ati pe o jẹ ifosiwewe eewu fun awọn arun ti o ni ibatan thromboembolism.
Iwọn FIB coagulation le pọ si ni ọpọlọpọ awọn arun, jiini ti o wọpọ tabi awọn okunfa iredodo, awọn lipids ẹjẹ giga, titẹ ẹjẹ
Ga, arun ọkan iṣọn-alọ ọkan, itọ-ọgbẹ suga, iko, arun ti ara asopọ, arun ọkan, ati awọn èèmọ buburu.nigba ijiya lati gbogbo awọn arun ti o wa loke le ja si iṣẹlẹ ti awọn didi ẹjẹ.Nitorinaa, iye FIB coagulation ẹjẹ ti o ga n tọka si ipo ti coagulation ẹjẹ giga.
Iwọn fibrinogen ti o ga julọ tumọ si pe ẹjẹ wa ni ipo hypercoagulability ati pe o ni itara si thrombosis.Fibrinogen ni a tun mọ ni ifosiwewe coagulation I. Boya o jẹ coagulation endogenous tabi coagulation exogenous, igbesẹ ikẹhin ti fibrinogen yoo mu awọn fibroblasts ṣiṣẹ.Awọn ọlọjẹ ti wa ni idapọ diẹdiẹ sinu nẹtiwọọki kan lati ṣe awọn didi ẹjẹ, nitorinaa fibrinogen duro fun iṣẹ ṣiṣe ti coagulation ẹjẹ.
Fibrinogen jẹ iṣelọpọ nipasẹ ẹdọ ati pe o le gbega ni ọpọlọpọ awọn arun.Jiini ti o wọpọ tabi awọn okunfa iredodo pẹlu awọn lipids ti o ga, titẹ ẹjẹ ti o ga, arun ọkan iṣọn-alọ ọkan, diabetes, iko, arun àsopọ ara, arun ọkan, ati awọn Tumor buburu yoo dide.Lẹhin iṣẹ abẹ nla, nitori pe ara nilo lati ṣe iṣẹ hemostasis, yoo tun ṣe alekun ilosoke ti fibrinogen fun iṣẹ hemostasis.
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