Ukuqulunqwa kwe-thrombus kuhambelana nokulimala kwe-vascular endothelial, i-hypercoagulability yegazi, kunye nokucotha kwegazi.Ke ngoko, abantu abanale miba mithathu yomngcipheko bathambekele kwi-thrombus.

1. Abantu abanokulimala kwe-vascular endothelial, njengabo baye bafumana i-vascular puncture, i-catheterization ye-venous, njl., ngenxa ye-endothelium ye-vascular eyonakalisiweyo, i-collagen fibers evezwe phantsi kwe-endothelium ingenza i-platelet kunye ne-coagulation factor, enokuthi iqalise i-endogenous coagulation.Inkqubo ibangela i-thrombosis.

2. Abantu abagazi labo likwimeko ye-hypercoagulable, njengezigulane ezine-tumor ezimbi, i-systemic lupus erythematosus, i-trauma enzima okanye utyando olukhulu, banemiba engaphezulu ye-coagulation egazini labo kwaye kunokwenzeka ukuba badibanise ngaphezu kwegazi eliqhelekileyo, ngoko ke banokwenzeka kakhulu. ukwenza i-thrombosis.Omnye umzekelo ngabantu abathatha izithintelo zokukhulelwa, i-estrogen, i-progesterone kunye nezinye iziyobisi ixesha elide, umsebenzi wabo we-coagulation yegazi uya kuchaphazeleka, kwaye kulula ukwenza amahlule egazi.

3. Abantu abanegazi elihamba kancinane, njengabo bahlala ixesha elide bedlala i-mahjong, ukubukela i-TV, ukufunda, ukuthatha iklasi yezoqoqosho, okanye ukuhlala ebhedini ixesha elide, ukungabikho kokwenza umthambo kunokubangela ukuhamba kwegazi ukucotha okanye ukudodobala Ukwenziwa kwee-vortices kutshabalalisa ukuhamba kwegazi okuqhelekileyo, okuya kwandisa ithuba leeplatelet, iiseli ze-endothelial kunye ne-coagulation factor to contact, kwaye kulula ukwenza i-thrombus.