I-Anticoagulation yinkqubo yokunciphisa ukubunjwa kwe-fibrin thrombus ngokusetyenziswa kweziyobisi ze-anticoagulant ukunciphisa inkqubo ye-intrinsic pathway kunye ne-intrinsic coagulation pathway.

Iyeza elichasayo kukuthatha iziyobisi ezichasene neplatelet ukunciphisa ukunamathela kunye nomsebenzi wokudibanisa iiplatelet, ngaloo ndlela ukunciphisa inkqubo yokwakheka kweplatelet thrombus.Kwinkqubo yeklinikhi, iziyobisi ezisetyenziswa ngokuqhelekileyo ze-anticoagulant ziquka i-warfarin kunye ne-heparin, enciphisa ithuba lokwakheka kwe-fibrinogen thrombus ngeendlela ezahlukeneyo ze-anticoagulant.Ngokomzekelo, i-warfarin idla ngokusetyenziswa kunyango lwe-anticoagulant emva kotyando lwevalvu yentliziyo, kwaye i-heparin isetyenziswa rhoqo kunyango lwe-thrombosis ye-venous esezantsi.

Izidakamizwa eziqhelekileyo ze-antiplatelet ziquka i-aspirin, i-Plavix, njl. La machiza anokuthintela ukuhlanganiswa kweplatelet ngokusebenzisa izixhumanisi ezahlukeneyo, ngaloo ndlela ukuthintela ukubunjwa kwe-platelet thrombus.Ngokonyango, isetyenziselwa ukuthintela isifo senhliziyo, isifo se-cerebral thrombosis kunye nezinye izifo.