I-FIB sisishunqulelo sesiNgesi se-fibrinogen, kwaye i-fibrinogen yi-coagulation factor.Ixabiso eliphezulu le-FIB coagulation lithetha ukuba igazi likwimeko ye-hypercoagulable, kwaye i-thrombus yenziwa lula.

Emva kokuba inkqubo yokudibanisa komntu isebenze, i-fibrinogen iba yi-fibrin monomer phantsi kwesenzo se-thrombin, kwaye i-fibrin monomer inokudityaniswa ibe yi-fibrin polymer, eluncedo ekwenzeni ihlwili legazi kwaye idlala indima ebalulekileyo kwinkqubo yokudibanisa.

I-Fibrinogen idityaniswe ikakhulu yi-hepatocytes kwaye iyiprotheyini ene-coagulation function.Ixabiso layo eliqhelekileyo liphakathi kwe-2 ~ 4qL.I-Fibrinogen yinto enxulumene ne-coagulation, kwaye ukunyuka kwayo kudla ngokuphindaphindiweyo ukusabela okungaqhelekanga komzimba kwaye kungumngcipheko wezifo ezinxulumene ne-thromboembolism.
Ixabiso le-FIB ye-Coagulation inokunyuswa kwizifo ezininzi, izinto eziqhelekileyo zemfuza okanye ezivuthayo, i-lipids ephezulu yegazi, uxinzelelo lwegazi.

Isifo senhliziyo esiphakamileyo, isifo seswekile, isifo sephepha, isifo se-tissue esihlangeneyo, isifo senhliziyo, kunye namathumba anobungozi.xa ukubandezeleka kuzo zonke ezi zifo zingasentla kunokukhokelela ekubeni kwenzeke amahlwili egazi.Ke ngoko, i-high blood coagulation ye-FIB ixabiso libhekisa kwimeko ye-blood coagulation ephezulu.