I-APTT imele i-activated partial thromboplastin ixesha, elibhekisa kwixesha elifunekayo ukongeza inxalenye ye-thromboplastin kwiplasma evavanyiweyo kunye nokujonga ixesha elifunekayo kwi-plasma coagulation.I-APTT luvavanyo lokuhlola olunovakalelo nolona luxhaphakileyo ukumisela inkqubo ye-endogenous coagulation.Uluhlu oluqhelekileyo luyi-31-43 imizuzwana, kunye nemizuzwana ye-10 ngaphezu kolawulo oluqhelekileyo lunokubaluleka kwekliniki.Ngenxa yeyantlukwano phakathi kwabantu, ukuba iqondo lokufinyezwa kwe-APTT lincinci kakhulu, linokuba yinto eqhelekileyo, kwaye akukho mfuneko yokuba novalo olugqithisileyo, kwaye ukuphononongwa rhoqo kwanele.Ukuba uziva ungaphilanga, bonana nogqirha kwangethuba.

Ukunciphisa i-APTT kubonisa ukuba igazi likwimeko ye-hypercoagulable, eqhelekileyo kwizifo ze-cardiovascular and cerebrovascular thrombotic, ezifana ne-cerebral thrombosis kunye nesifo senhliziyo.

1. I-Cerebral thrombosis

Izigulane ezine-APTT ezimfutshane kakhulu ziyakwazi ukuphuhlisa i-cerebral thrombosis, eqhelekileyo kwizifo ezinxulumene ne-hypercoagulation yegazi ebangelwa utshintsho kumacandelo egazi, njenge-hyperlipidemia.Ngeli xesha, ukuba iqondo le-cerebral thrombosis lincinci, kuphela iimpawu zokungonelanga kwegazi ukuya kwingqondo ziya kuvela, ezifana nesiyezi, intloko ebuhlungu, isicaphucaphu kunye nokugabha.Ukuba iqondo le-cerebral thrombosis linzima ngokwaneleyo ukuba libangele i-cerebral parenchymal ischemia enzima, iimpawu zeklinikhi ezifana nokungahambi kakuhle kwamalungu, ukukhubazeka kwentetho, kunye nokungakwazi ukuzibamba kuya kuvela.Kwizigulane ezine-acute cerebral thrombosis, i-oxygen inhalation kunye nenkxaso yokuphefumula ngokuqhelekileyo isetyenziselwa ukwandisa ukunikezelwa kwe-oxygen.Xa iimpawu zesigulane zisongela ubomi, i-thrombolysis esebenzayo okanye utyando lokungenelela kufuneka lwenziwe ukuvula imithwalo yegazi ngokukhawuleza.Emva kokuba iimpawu ezibalulekileyo ze-cerebral thrombosis zithotywe kwaye zilawulwe, isigulane kufuneka siqhubeke sinamathela kwimikhwa emihle yokuphila kwaye sithathe amayeza exesha elide phantsi kwesikhokelo soogqirha.Kunconywa ukuba udle ukutya okunetyuwa kunye ne-fat-fat ngexesha lokubuyisela, udle imifuno kunye neziqhamo ezininzi, ugweme ukutya ukutya okuphezulu kwe-sodium njenge-bacon, pickles, ukutya okusemathinini, njl., kwaye ugweme ukutshaya notywala.Yenza umthambo ngobungcathu xa imeko yakho yomzimba ikuvumela.

2. Isifo sentliziyo

Ukunciphisa i-APTT kubonisa ukuba isigulane sinokubandezeleka ngenxa yesifo senhliziyo, esihlala sibangelwa yi-coronary blood hypercoagulation ekhokelela kwi-stenosis okanye ukuvaleka kwe-lumen yesitya, okukhokelela kwi-ischemia ye-myocardial, i-hypoxia, kunye ne-necrosis ehambelanayo.Ukuba iqondo lokuvaleka komthambo we-coronary liphezulu ngokwentelekiso, isigulana sisenokungabi nazimpawu zicacileyo zeklinikhi kwindawo yokuphumla, okanye sinokufumana kuphela ukungonwabi okufana nokuxinana kwesifuba kunye neentlungu zesifuba emva kwemisebenzi.Ukuba iqondo lokuvaleka komthambo we-coronary linzima, umngcipheko we-myocardial infarction uyanda.Izigulana zisenokuba neentlungu zesifuba, ukuxinezeleka kwesifuba, kunye nokuphefumla kancinci xa ziphumle okanye zichwayitile ngokweemvakalelo.Intlungu inokusasazeka kwezinye iindawo zomzimba kwaye iqhubeke ngaphandle kokukhululeka.Kwizigulane ezine-acute yokuqala ye-coronary heart disease, emva kokulawulwa kwe-sublingual ye-nitroglycerin okanye i-isosorbide dinitrate, jonga ugqirha ngokukhawuleza, kwaye ugqirha uvavanya ukuba i-coronary stent implantation okanye i-thrombolysis iyadingeka ngokukhawuleza.Emva kwesigaba esinzima, unyango lwexesha elide lwe-antiplatelet kunye ne-anticoagulant luyafuneka.Emva kokukhutshwa esibhedlele, isigulane kufuneka sibe netyuwa ephantsi kunye nokutya okunamafutha aphantsi, ukuyeka ukutshaya nokusela, ukuzivocavoca ngokufanelekileyo, kwaye ubeke ingqalelo ekuphumleni.