I-D-dimer ivela kwi-clot ye-fibrin edibeneyo edibeneyo echithwa yi-plasmin.Ikakhulu ibonisa umsebenzi we-lytic we-fibrin.Isetyenziswa kakhulu ekuxilongweni kwe-venous thromboembolism, i-thrombosis ye-vein deep kunye ne-pulmonary embolism ekusebenzeni kweklinikhi.Uvavanyo lomgangatho we-D-dimer alinayo, ukuba uvavanyo lobungakanani kufuneka lube ngaphantsi kwe-200μg/L.

Ukunyuka kwe-D-dimer okanye iziphumo zovavanyo ezilungileyo zihlala zibonwa kwizifo ezinxulumene ne-hyperfibrinolysis yesibini, njenge-hypercoagulable state, i-comagulation ye-intravascular coagulation esasazwayo, isifo sezintso, ukwaliwa kwamalungu, kunye nonyango lwe-thrombolytic.Ukongeza, xa kukho i-thrombosis esebenzayo kwimithambo yegazi yomzimba, okanye izifo ezihamba kunye nomsebenzi we-fibrinolytic, i-D-dimer nayo iya kwandiswa kakhulu.Izifo eziqhelekileyo ezifana ne-myocardial infarction, i-pulmonary embolism, i-thrombosis ephantsi ye-vein deep, i-cerebral infarction njl.;ezinye usulelo, utyando, izifo ithumba, kunye necrosis izicubu kwakhona kukhokelela ekwandeni D-dimer;Ukongeza, ezinye izifo ezizimele zomntu, ezifana ne-rheumatic endocarditis, i-rheumatoid arthritis, i-systemic Lupus erythematosus, njl., zinokubangela ukwanda kwe-D-dimer.

Ukongeza ekuxilongeni izifo, ukufunyanwa kobuninzi be-D-dimer kunokubonakalisa ngokobungakanani umphumo we-thrombolytic wamachiza ekusebenzeni kweklinikhi.Iinkalo zezifo, njl., zonke ziluncedo.

Kwimeko ye-D-dimer ephakamileyo, umzimba usengozini enkulu ye-thrombosis.Ngeli xesha, isifo esiphambili kufuneka sifunyanwe ngokukhawuleza, kwaye inkqubo yokukhusela i-thrombosis kufuneka iqalwe ngokuhambelana nenqaku le-DVT.Amanye amachiza anokukhethwa kunyango lwe-anticoagulation, njengenaliti ephantsi kwe-molecular weight heparin calcium okanye i-rivaroxaban, enempembelelo ethile yokuthintela ekubunjweni kwe-thrombosis.Abo banezilonda ze-thrombotic kufuneka benze i-thrombolytic tumor ngokukhawuleza ngexesha legolide, kwaye Rhoqo uphonononge i-D-dimer.