Isizathu se-thrombosis sibandakanya i-lipids ephezulu yegazi, kodwa ayingawo onke amahlwili egazi abangelwa yi-lipids ephezulu yegazi.Oko kukuthi, imbangela ye-thrombosis ayikho yonke into ngenxa yokuqokelela izinto ze-lipid kunye ne-viscosity ephezulu yegazi.Omnye umngcipheko kukudityaniswa kweeplatelet, iiseli zomzimba ezijiyisa igazi.Ke ukuba sifuna ukuqonda ukuba i-thrombus yenziwa njani, kufuneka siqonde ukuba kutheni iiplatelet zihlangana?
Ngokuqhelekileyo, umsebenzi ophambili weeplatelet kukubumbana.Xa ulusu lwethu luphazamisekile, kusenokubakho ukopha ngeli xesha.Umqondiso wokuphuma kwegazi uya kudluliselwa kwinkqubo ephakathi.Ngeli xesha, iiplatelet ziya kubuthana kwindawo yesilonda kwaye ziqhubeke ziqokelela kwisilonda, ngaloo ndlela zivimbela i-capillaries kunye nokufezekisa injongo ye-hemostasis.Emva kokuba sonzakele, ukhoko lwegazi lusenokwenziwa enxebeni, eliye lenzeka emva kokudityaniswa kweeplatelet.
Ukuba le meko ingentla yenzeka kwimithambo yethu yegazi, ixhaphake kakhulu ukuba imithambo yegazi yonakele.Ngeli xesha, iiplatelet ziya kubuthana kwindawo eyonakalisiweyo ukufezekisa injongo ye-hemostasis.Ngeli xesha, imveliso ye-platelet aggregation ayikho i-scab yegazi, kodwa i-thrombus esithetha ngayo namhlanje.Ngoko ngaba i-thrombosis emithanjeni yegazi ibangelwa ngumonakalo wegazi?Ngokuqhelekileyo, i-thrombus yenziwe ngokwenene ngokukrazuka komthambo wegazi, kodwa akusiyo imeko yokuphulwa komthambo wegazi, kodwa umonakalo wodonga lwangaphakathi lomthambo wegazi.
Kwii-atherosclerotic plaques, ukuba ukuphuka kwenzeka, amanqatha afakwe ngeli xesha angabonakaliswa egazini.Ngale ndlela, iiplatelets ezisegazini zitsalwa.Emva kokuba iiplatelet zifumene umqondiso, ziya kuqhubeka zidibanisa apha kwaye ekugqibeleni zenze i-thrombus.
Ukuyibeka ngokulula, i-lipids ephezulu yegazi ayiyona sizathu esithe ngqo se-thrombosis.I-Hyperlipidemia kukuba kukho iilipids ezininzi kwimithambo yegazi, kwaye i-lipids ayidibanisi ibe ngamaqoqo emithanjeni yegazi.Nangona kunjalo, ukuba inqanaba le-lipid yegazi liyaqhubeka nokunyuka, kunokwenzeka ukuba i-atherosclerosis kunye ne-plaque iya kuvela.Emva kokuba ezi ngxaki zenzeke, kunokubakho ukuphuka, kwaye i-thrombus ilula ukwenza ngeli xesha.