I-D-Dimer njengesalathisi sezifo ezahlukeneyo:

Ngenxa yobudlelwane obusondeleyo phakathi kwenkqubo ye-coagulation kunye nokuvuvukala, umonakalo we-endothelial, kunye nezinye izifo ezingenayo i-thrombotic ezifana nokusuleleka, utyando okanye ukwenzakala, ukungaphumeleli kwentliziyo, kunye nezicubu ezinobungozi, ukwanda kwe-D-Dimer kudla ngokubonwa.Kuphando, kuye kwafunyaniswa ukuba i-prognosis ixhaphake kakhulu kwezi zifo iseyi-thrombosis, i-DIC, njl.Ke i-D-Dimer ingasetyenziswa njengophawu olubanzi noluvakalelo lovavanyo lwezifo.

1.Kwizigulane zomhlaza, izifundo ezininzi ziye zafumanisa ukuba izinga lokusinda le-1-3 leminyaka yezigulane ezinobungozi ezine-D-Dimer ephakamileyo ziphantsi kakhulu kunezo zine-D-Dimer eqhelekileyo.I-D-Dimer ingasetyenziselwa njengesalathisi sokuvavanya ukuxilongwa kwezigulane ezinobungozi ezinobungozi.

I-2.Kwizigulane ze-VTE, izifundo ezininzi ziqinisekisile ukuba i-D-Dimer izigulane ezintle ngexesha le-anticoagulation zine-2-3 ingozi ephezulu yokuphindaphinda kwe-thrombotic elandelayo xa kuthelekiswa nezigulane ezimbi.Olunye uhlalutyo lwe-meta lwabathathi-nxaxheba be-1818 kwizifundo ze-7 lubonise ukuba i-D-Dimer engaqhelekanga yenye yezinto eziphambili zokuphindaphinda kwe-thrombotic kwizigulane ze-VTE, kwaye i-D-Dimer ifakwe kwiimodeli ezininzi ze-VTE zokuphindaphinda ingozi.

I-3.Kwizigulane ezithatha indawo ye-valve ye-mechanical (MHVR), uphononongo olulandelwayo lwexesha elide lwabathathi-nxaxheba be-618 lubonise ukuba izigulane ezinamazinga angaqhelekanga e-D-Dimer ngexesha le-warfarin emva kokuba i-MHVR inomngcipheko weziganeko ezimbi malunga namaxesha angama-5 aphezulu kunezo. ngamanqanaba aqhelekileyo.Uhlalutyo lwe-multivariate correlation luqinisekisile ukuba amanqanaba e-D-Dimer ayezibikezelo ezizimeleyo ze-thrombosis okanye iziganeko ze-cardiovascular ngexesha lokulwa ne-anticoagulation.

I-4.Izigulane ezine-fibrillation ye-atrial (AF), i-D-Dimer inokuqikelela iziganeko ze-thrombotic kunye ne-cardiovascular ngexesha lokuchasana komlomo.Uphononongo olulindelekileyo lwezigulane ze-269 ezine-fibrillation ye-atrial elandelwayo malunga neminyaka eyi-2 ibonise ukuba ngexesha lokulwa nomlomo, malunga ne-23% yezigulane eziye zadibana nomgangatho we-INR zibonise amanqanaba e-D-Dimer angaqhelekanga, ngelixa izigulane ezinezinga elingaqhelekanga le-D-Dimer zine-15.8 kunye Amaxesha e-7.64 aphezulu umngcipheko we-thrombotic kunye neziganeko ze-cardiovascular concomitant xa kuthelekiswa nezigulane ezinezinga eliqhelekileyo le-D-Dimer, ngokulandelanayo.
Kwezi zifo okanye izigulana ezithile, i-D-Dimer ephezulu okanye ethe gqolo ibonisa ukuba imeko imbi okanye imbi kakhulu.