ISiseko seTheory yeSicelo se-D-Dimer


Umbhali: Ophumeleleyo   

1. Ukunyuka kwe-D-Dimer kubonisa ukusetyenziswa kweenkqubo ze-coagulation kunye ne-fibrinolysis emzimbeni, obonisa isimo esiphezulu sokuguqulwa.
I-D-Dimer ayinayo kwaye ingasetyenziselwa ukukhutshwa kwe-thrombus (elona xabiso liphambili lekliniki);I-D-Dimer enhle ayinakungqina ukubunjwa kwe-thromboembolus, kwaye ukuzimisela okuthe ngqo ukuba i-thromboembolus yenziwe kusafuneka isekelwe kwisimo sokulingana kwezi nkqubo zimbini.
2. I-half-life ye-D-Dimer yi-7-8 iiyure kwaye inokubonwa kwiiyure ezi-2 emva kwe-thrombosis.Olu phawu lunokuhambelana kakuhle nokusebenza kweklinikhi kwaye aluyi kuba nzima ukulibona ngenxa yesiqingatha sobomi obufutshane, kwaye aluyi kulahlekelwa ukubaluleka kokubeka iliso ngenxa yesiqingatha sobomi obude.
3. I-D-Dimer inokuhlala izinzile ubuncinane kwiiyure ze-24-48 kwiisampuli zegazi ezifihliweyo, evumela ukuba i-in vitro ifumaneke umxholo we-D-Dimer ukubonisa ngokuchanekileyo izinga le-D-Dimer emzimbeni.
4. Indlela yokusebenza ye-D-Dimer isekelwe kwi-antigen antibody reactions, kodwa indlela ekhethekileyo iyahluka kwaye ayihambelani.Ama-antibodies kwii-reagents ahlukeneyo, kwaye iziqwenga ze-antigen ezifunyenweyo azihambelani.Xa ukhetha uphawu kwilabhoratri, kuyimfuneko ukwahlula.