I-Thrombosis yindlela nje eqhelekileyo yokujika kwegazi emzimbeni.Ngaphandle kwe-thrombus, abantu abaninzi banokufa "ngenxa yokulahlekelwa kwegazi eligqithiseleyo".
Ngamnye wethu uye wonzakele kwaye wopha, njengenxeba elincinane emzimbeni, eliya kuthi liphume ngokukhawuleza.Kodwa umzimba womntu uya kuzikhusela.Ukuze kuthintelwe ukopha de kube sekufeni, igazi liya kuthi chu kancinci kwindawo yokopha, oko kukuthi, igazi liya kwenza i-thrombus kumthambo wegazi owonakele.Ngale ndlela, akusayi kuphinda ukopha.
Xa ukopha kuyeka, umzimba wethu uya kunyibilika kancinci kancinci i-thrombus, nto leyo evumela igazi ukuba lijikeleze kwakhona.
Indlela evelisa i-thrombus ibizwa ngokuba yi-coagulation system;indlela yokususa i-thrombus ibizwa ngokuba yi-fibrinolytic system.Emva kokuba umthambo wegazi wonakaliswe emzimbeni womntu, inkqubo ye-coagulation isebenze ngokukhawuleza ukukhusela ukuqhubeka ukopha;emva kokuba i-thrombus isenzeka, inkqubo ye-fibrinolytic ephelisa i-thrombus iya kwenziwa isebenze ukunyibilikisa ihlwili legazi.
Ezi nkqubo zimbini zilungelelaniswa ngokuguquguqukayo, ziqinisekisa ukuba igazi alijiki kwaye alophi kakhulu.
Nangona kunjalo, izifo ezininzi ziya kukhokelela ekusebenzeni okungaqhelekanga kwenkqubo ye-coagulation, kunye nomonakalo kwi-intima yomkhumbi wegazi, kunye ne-blood stasis iya kwenza inkqubo ye-fibrinolytic emva kwexesha okanye ingonelanga ukunyibilikisa i-thrombus.
Ngokomzekelo, kwi-acute myocardial infarction, kukho i-thrombosis kwintliziyo yegazi.Imeko yemithambo yegazi imbi kakhulu, kukho umonakalo ohlukeneyo we-intima, kwaye kukho i-stenosis, edityaniswa nokuhamba kwegazi, akukho ndlela yokunyibilikisa i-thrombus, kwaye i-thrombus iya kuba nkulu kwaye ibe nkulu.
Ngokomzekelo, kubantu abalele ixesha elide, ukuhamba kwegazi lendawo emilenzeni kuyancipha, i-intima yemithambo yegazi yonakaliswe, kwaye i-thrombus yenziwa.I-thrombus iya kuqhubeka nokunyibilika, kodwa isantya sokunyibilika asikhawulezi ngokwaneleyo, inokuwa, iphinde ibuyele kumthambo we-pulmonary ecaleni kwenkqubo yegazi, ibambeke kumthambo we-pulmonary, kwaye ibangele i-pulmonary embolism, ekwabulalayo.
Ngeli xesha, ukwenzela ukuba kuqinisekiswe ukhuseleko lwezigulane, kuyimfuneko ukwenza i-thrombolysis eyenziwe ngobuchule kunye nokujova izidakamizwa ezisetyenziselwa ukukhuthaza i-thrombolysis, njenge "urokinase".Nangona kunjalo, i-thrombolysis ngokubanzi ifuna ukwenziwa ngexesha elifutshane le-thrombosis, njengeeyure ezi-6.Ukuba ithatha ixesha elide, ayiyi kunyibilika.Ukuba unyusa ukusetyenziswa kweziyobisi ze-thrombolytic ngeli xesha, kunokubangela ukopha kwamanye amalungu omzimba.
I-thrombus ayinakuchithwa.Ukuba ayivalwanga ngokupheleleyo, i-"stent" ingasetyenziselwa "ukutsala uvule" umthambo wegazi ovalekileyo ukuqinisekisa ukuhamba kakuhle kwegazi.
Nangona kunjalo, ukuba umthambo wegazi uvaliwe ixesha elide, uya kubangela i-ischemic necrosis yezakhiwo ezibalulekileyo zezicubu.Ngeli xesha, kuphela "ngokugqithisa" enye imithambo yegazi inokungeniswa "ukunkcenkceshela" le nxalenye yezicubu eziphulukene negazi.
Ukopha kunye ne-coagulation, i-thrombosis kunye ne-thrombolysis, yibhalansi ethambileyo egcina imisebenzi ye-metabolic yomzimba.Ayisiyiyo loo nto kuphela, kukho ibhalansi ezininzi ezikrelekrele kumzimba womntu, njenge-nerve sympathetic ne-vagus nerve, egcina ukonwaba kwabantu ngaphandle kokonwaba kakhulu;i-insulin kunye neglucagon zilawula ibhalansi yeswekile yegazi;I-calcitonin kunye nehomoni ye-parathyroid ilawula iswekile yegazi labantu.
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