Igazi elijijekileyo alikho ukuba lilungile okanye libi.I-blood coagulation inoluhlu lwexesha eliqhelekileyo.Ukuba ikhawuleza kakhulu okanye icotha kakhulu, iya kuba yingozi kumzimba womntu.

I-coagulation yegazi iya kuba phakathi koluhlu oluthile oluqhelekileyo, ukwenzela ukuba ungabangeli ukuphuma kwegazi kunye nokwakheka kwe-thrombus emzimbeni womntu.Ukuba i-blood coagulation ikhawuleza kakhulu, ngokuqhelekileyo ibonisa ukuba umzimba womntu ukwimeko ye-hypercoagulable, kwaye izifo ze-cardiovascular and cerebrovascular zivame ukwenzeka, ezifana ne-cerebral infarction kunye ne-Myocardial infarction, i-thrombosis ye-venous ephantsi kunye nezinye izifo.Ukuba igazi lomguli lijija ngokucothayo, kusenokwenzeka ukuba lijiyile, lidla ngokuba nezifo ezophayo, ezifana nehemophilia, yaye kwiimeko ezimandundu, liya kushiya amalungu angasebenzi kakuhle nezinye izinto ezimbi.

Umsebenzi olungileyo we-thrombin ubonisa ukuba iiplatelet zisebenza kakuhle kwaye zisempilweni kakhulu.I-Coagulation ibhekisela kwinkqubo yokutshintsha kwegazi ukusuka kwimeko ehambayo ukuya kwi-gel state, kwaye ingundoqo yayo yinkqubo yokuguqula i-fibrinogen e-soluble ibe yi-fibrinogen e-insoluble kwi-plasma.Ngengqiqo emxinwa, xa imithambo yegazi yonakele, umzimba uvelisa izinto ezidityanisiweyo, ezithi zisebenze ukuze zivelise ithrombin, ethi ekugqibeleni iguqule ifibrinogen ibe yifibrin, ngaloo ndlela ikhuthaza ukuqina kwegazi.I-coagulation ngokubanzi ikwabandakanya umsebenzi weplatelet.