I-D-dimer yimveliso yokuthotywa kwe-fibrin, ehlala isetyenziswa kwiimvavanyo zomsebenzi we-coagulation.Umgangatho wayo oqhelekileyo ngu-0-0.5mg/L.Ukunyuka kwe-D-dimer kunokuhambelana nezinto eziphilayo ezifana nokukhulelwa, okanye Inxulumene nezinto ze-pathological ezifana nezifo ze-thrombotic, izifo ezithathelwanayo, kunye nezicubu ezinobungozi.Kucetyiswa ukuba izigulana ziye kwisebe lesibhedlele le-hematology ukufumana unyango kwangethuba.

1. Imiba yePhysiology:
Ngexesha lokukhulelwa, amanqanaba e-hormone emzimbeni aya kutshintsha, nto leyo enokukhuthaza ukuthotywa kwefibrin ukuvelisa i-D-dimer, enokubangela ukwanda kwe-D-dimer egazini, kodwa ngokuqhelekileyo ingaphakathi kuluhlu oluqhelekileyo okanye ukunyuka kancinane. yinto eqhelekileyo ye-physiological phenomenon kwaye ngokubanzi ayifuni unyango olukhethekileyo.

2. Izinto zePathological:
1. Isifo seThrombotic: Ukuba kukho isifo se-thrombotic emzimbeni, njenge-vein thrombosis enzulu, i-pulmonary embolism, njl., inokukhokelela ekusebenzeni okungaqhelekanga kwegazi, ukwenza igazi libe kwimeko ye-hypercoagulable, kwaye ivuselele inkqubo ye-fibrinolytic hyperactivity, okubangela i-D-dimerization Ukwanda kweemveliso zokunciphisa i-fibrin ezifana nomzimba kunye nezinye i-fibrin, ezikhokelela ekunyuseni kwe-D-dimer egazini.Ngeli xesha, phantsi kolawulo logqirha, i-recombinant streptokinase ye-injection, i-urokinase ye-injection kunye nezinye iziyobisi zingasetyenziselwa unyango ukuvimbela ukubunjwa kwe-thrombus;

2. Izifo ezithathelwanayo: Ukuba kukho isifo esibi emzimbeni, njenge-sepsis, i-pathogenic microorganisms egazini ikhula ngokukhawuleza emzimbeni, ihlasele izicubu kunye namalungu omzimba wonke, itshabalalise inkqubo ye-microvascular system, kwaye yenze i-capillary thrombosis. emzimbeni wonke.Kuya kukhokelela ekuhanjisweni kwe-intravascular coagulation kuwo wonke umzimba, ukuvuselela ukuphuculwa komsebenzi we-fibrinolytic emzimbeni, kwaye kubangele ukwanda kwe-D-dimer egazini.Ngeli xesha, isigulana sinokusebenzisa iziyobisi ezichasene nezifo ezifana ne-cefoperazone sodium kunye ne-sulbactam sodium kwi-injection njengoko kuyalelwa ngugqirha.;

3. Amathumba anobungozi: Iiseli ze-tumor ezinobungozi ziya kukhupha i-procoagulant substance, ivuselele ukubunjwa kwe-thrombus emithanjeni yegazi, kwaye isebenze inkqubo ye-fibrinolytic, okubangelwa ukwanda kwe-D-dimer egazini.Ngeli xesha, inaliti ye-paclitaxel, i-Chemotherapy enenaliti yamachiza afana ne-cisplatin.Ngelo xesha, unokwenza utyando ukususa i-tumor ngokwengcebiso kagqirha, ekulungele ukubuyiswa kwesi sifo.