Emva kokuba i-thrombosis yenziwe, isakhiwo sayo sitshintsha phantsi kwesenzo se-fibrinolytic system kunye nokutshatyalaliswa kwegazi kunye nokuvuselelwa komzimba.
Kukho iintlobo ezi-3 eziphambili zotshintsho lokugqibela kwi-thrombus:
1. Thambisa, nyibilikisa, mfunxa
Emva kokuba i-thrombus yenziwe, i-fibrin kuyo ithatha inani elikhulu le-plasmin, ukwenzela ukuba i-fibrin kwi-thrombus ibe yi-polypeptide e-soluble kwaye iyancibilika, kwaye i-thrombus iyancipha.Ngelo xesha, ngenxa yokuba i-neutrophils kwi-thrombus iyahlukana kwaye ikhulule i-proteolytic enzymes, i-thrombus inokuchithwa kwaye ithambe.
I-thrombus encinci iyanyibilika kwaye iyancibilika, kwaye inokufunxwa ngokupheleleyo okanye ihlanjwe ligazi ngaphandle kokushiya umkhondo.
Inxalenye enkulu ye-thrombus iyathamba kwaye iwa ngokulula ngokuhamba kwegazi ukuze ibe yi-embolus.I-emboli ivimba isitya segazi esihambelanayo kunye nokuhamba kwegazi, okunokubangela ukuba i-embolism, ngelixa inxalenye eseleyo ihlelwe.
2. Ukusetyenziswa kwemitshini kunye nokuRecanalization
I-thrombi enkulu ayilula ukuyinyibilika kwaye ifunxe ngokupheleleyo.Ngokuqhelekileyo, kwiintsuku ezi-2 ukuya kwezi-3 emva kokubunjwa kwe-thrombus, izicubu ze-granulation zikhula ukusuka kwi-intima ye-vascular eyonakalisiweyo apho i-thrombus ifakwe khona, kwaye ngokuthe ngcembe ithatha indawo ye-thrombus, ebizwa ngokuba yintlangano ye-thrombus.
Xa i-thrombus ilungelelanisiwe, i-thrombus iyancipha okanye inyibilike ngokuyinxenye, kwaye i-fissure ivame ukubunjwa ngaphakathi kwe-thrombus okanye phakathi kwe-thrombus kunye nodonga lwesitya, kwaye umphezulu ugutyungelwe ngokunyuka kweeseli ze-vascular endothelial, kwaye ekugqibeleni enye okanye imithambo encinci yegazi. ezinxibelelana nomthambo wokuqala wegazi zenziwa.Ukuhlaziywa kokuhamba kwegazi kubizwa ngokuba kukuhlaziywa kwakhona kwe-thrombus.
3. Ukubalwa
Inani elincinci le-thrombi elingenakuchithwa ngokupheleleyo okanye lilungelelaniswe linokuthi lihlanjululwe kwaye libalwe ngeetyuwa ze-calcium, zenze amatye anzima akhoyo kwimithambo yegazi, ebizwa ngokuba yi-phleboliths okanye i-arterioliths.
Impembelelo yamahlwili egazi emzimbeni
I-Thrombosis ineempembelelo ezimbini emzimbeni.
1. Kwicala lokudibanisa
I-Thrombosis yenziwa kwisitya segazi esiqhekezayo, esinomphumela we-hemostatic;I-thrombosis yemithambo encinci yegazi ejikeleze i-foci evuthayo inokuthintela ukusasazeka kwebhaktheriya ye-pathogenic kunye ne-toxins.
2. Ngaphantsi
Ukubunjwa kwe-thrombus kwisitya segazi kunokuthintela umthambo wegazi, kubangela izicubu kunye ne-organ ischemia kunye ne-infarction;
I-Thrombosis yenzeka kwivalve yentliziyo.Ngenxa yokulungelelaniswa kwe-thrombus, i-valve iba yi-hypertrophic, i-shrunken, ibambelele, kwaye ilukhuni, okubangelwa isifo senhliziyo ye-valvular kunye nokuchaphazela ukusebenza kwentliziyo;
I-thrombus ilula ukuwa kwaye yenze i-embolus, ehamba kunye nokuhamba kwegazi kwaye yenza i-embolism kwezinye iindawo, okubangelwa i-infarction ebanzi;
I-microthrombosis enkulu kwi-microcirculation inokubangela ukopha okukhulu kwenkqubo kunye nokothuka.
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