1. I-Plasma D-dimer assay luvavanyo lokuqonda umsebenzi wesibini we-fibrinolytic.

Umgaqo wokuhlola: I-Anti-DD i-anti-monoclonal antibody igqunywe kumasuntswana e-latex.Ukuba kukho i-D-dimer kwiplasma ye-receptor, i-antigen-antibody reaction iya kwenzeka, kwaye amasuntswana e-latex aya kuhlanganisana.Nangona kunjalo, olu vavanyo lunokuba luhle nakuphi na ukopha kunye nokubunjwa kwehlwili legazi, ngoko ke lunobuntu obuphantsi kunye novakalelo oluphezulu.

2. Kukho imithombo emibini ye-D-dimer kwi-vivo

(1) I-hypercoagulable state kunye ne-hyperfibrinolysis yesibini;

(2) i-thrombolysis;

I-D-dimer ikakhulu ibonisa umsebenzi we-fibrinolytic.Ukunyuka okanye okulungileyo kubonwe kwi-hyperfibrinolysis yesibini, njenge-hypercoagulable state, i-coagulation ye-intravascular coagulation, isifo sezintso, ukulahlwa kwe-organ transplant, unyango lwe-thrombolytic, njl.

3. Ngethuba nje kukho i-thrombosis esebenzayo kunye nomsebenzi we-fibrinolytic kwimithambo yegazi yomzimba, i-D-dimer iya kwanda.

Umzekelo: i-myocardial infarction, i-cerebral infarction, i-pulmonary embolism, i-venous thrombosis, utyando, i-tumor, ukusabalalisa i-intravascular coagulation, usulelo kunye ne-necrosis yezicubu kunokukhokelela ekwandeni kwe-D-dimer.Ngokukodwa kubantu abadala kunye nezigulane ezibhedlele, ngenxa ye-bacteremia kunye nezinye izifo, kulula ukubangela ukudibanisa kwegazi okungaqhelekanga kwaye kukhokelela ekwandeni kwe-D-dimer.

4. Inkcazo ebonakaliswe ngu-D-dimer ayibhekiseli ekusebenzeni kwisifo esithile, kodwa kwiimpawu eziqhelekileyo ze-pathological zeli qela elikhulu lezifo kunye ne-coagulation kunye ne-fibrinolysis.

Ngokwethiyori, ukubunjwa kwe-fibrin edibeneyo yi-thrombosis.Nangona kunjalo, kukho izifo ezininzi zeklinikhi ezinokuthi zisebenze inkqubo ye-coagulation ngexesha lokwenzeka kunye nokuphuhliswa kwesi sifo.Xa i-fibrin edibeneyo edibeneyo iveliswa, inkqubo ye-fibrinolytic iya kwenziwa kwaye i-fibrin edibeneyo iya kuhlanjululwa nge-hydrolyzed ukukhusela "ukuqokelela" kwayo okukhulu.(i-thrombus ebalulekileyo ngokwekliniki), ekhokelela kwi-D-dimer ephakanyiswe ngokuphawulekayo.Ke ngoko, ukuphakama kwe-D-dimer akunyanzelekanga ukuba ibe yi-thrombosis ebaluleke kakhulu ekliniki.Kwezinye izifo okanye abantu, inokuba yinkqubo ye-pathological.