Izalathisi zovavanyo lomsebenzi we-Coagulation ziquka ixesha le-prothrombin (PT), ixesha le-thromboplastin elisebenzayo (APTT), ixesha le-thrombin (TT), i-fibrinogen (FIB), ixesha lokuvala (CT) kunye ne-International normalized ratio (INR), njl., izinto ezininzi zinokuba ekhethiweyo ukwenza ipakethe, ebizwa ngokuba yi-coagulation X.Ngenxa yeendlela ezahlukeneyo zokufumanisa ezisetyenziswa zizibhedlele ezahlukeneyo, uluhlu lwereferensi lukwahlukile.

Ixesha le-PT-prothrombin

I-PT ibhekisela ekongezeni i-tissue factor (i-TF okanye i-tishu thromboplastin) kunye ne-Ca2 + kwi-plasma ukuqalisa inkqubo ye-coagulation yangaphandle kwaye igcine ixesha lokudibanisa i-plasma.I-PT yenye yezona zinto zisetyenziswa ngokuqhelekileyo iimvavanyo zokuhlola kwiiklinikhi zokuvavanya umsebenzi we-extrinsic coagulation pathway.Ixabiso lereferensi eliqhelekileyo li-10 ukuya kwi-14 imizuzwana.

I-APTT-ixesha le-thromboplastin esebenzayo

I-APTT yongeza i-XII factor activator, i-Ca2 +, i-phospholipid kwi-plasma ukuze iqalise i-plasma endogenous coagulation pathway, kwaye igcine ixesha le-plasma coagulation.I-APTT ikwalolona vavanyo luqhelekileyo olusetyenziswayo kwiklinikhi ukuvavanya umsebenzi wendlela ye-intrinsic coagulation.Ixabiso lereferensi eliqhelekileyo liyi-32 ukuya kwi-43 imizuzwana.

INR - Umlinganiselo oQhelekileyo wamazwe ngamazwe

I-INR yi-ISI amandla omlinganiselo we-PT yesigulane esivavanyiweyo kwi-PT yolawulo oluqhelekileyo (i-ISI yinkcazo ye-sensitivity yamazwe ngamazwe, kwaye i-reagent ilinganiswe ngumenzi xa ishiya ifektri).Iplasma efanayo yavavanywa ngee-reagents ze-ISI ezahlukeneyo kwiilabhoratri ezahlukeneyo, kwaye iziphumo zexabiso le-PT zahluke kakhulu, kodwa amaxabiso alinganisiweyo e-INR ayefana, nto leyo eyenza ukuba iziphumo zithelekiseke.Ixabiso lereferensi eqhelekileyo ngu-0.9 ukuya ku-1.1.

Ixesha le-TT-thrombin

I-TT yongezwa kwe-thrombin eqhelekileyo kwi-plasma ukuze ibone isigaba sesithathu senkqubo yokudibanisa, ebonisa izinga le-fibrinogen kwi-plasma kunye nenani lezinto ezifana ne-heparin kwi-plasma.Ixabiso lereferensi eliqhelekileyo li-16 ukuya kwi-18 imizuzwana.

I-FIB-fibrinogen

I-FIB yongeza inani elithile le-thrombin kwi-plasma evavanyiweyo ukuguqula i-fibrinogen kwi-plasma ibe yi-fibrin, kwaye ubale umxholo we-fibrinogen ngokusebenzisa umgaqo we-turbidimetric.Ixabiso lereferensi eqhelekileyo yi-2 ukuya ku-4 g/L.

Imveliso yokuthotywa kwe-FDP-plasma fibrin

I-FDP ligama eliqhelekileyo leemveliso ezithotywayo eziveliswa emva kokuba i-fibrin okanye i-fibrinogen ichithwe phantsi kwesenzo se-plasmin eveliswe ngexesha le-hyperfibrinolysis.Ixabiso lereferensi eqhelekileyo yi-1 ukuya ku-5 mg/L.

Ixesha le-CT-coagulation

I-CT ibhekisela kwixesha apho igazi lishiya imithambo yegazi kwaye lidibanise kwi-vitro.Ikakhulu imisela ukuba ngaba izinto ezahlukeneyo zokudibanisa kwi-intrinsic coagulation pathway ziyasilela, nokuba umsebenzi wazo uqhelekile, okanye kukho ukwanda kwezinto ezilwa ne-anticoagulant.