PT e bolela nako ea prothrombin meriana, 'me APTT e bolela nako ea karolo ea thromboplastin e sebelisoang meriana.Ts'ebetso ea coagulation ea mali ea 'mele oa motho e bohlokoa haholo.Haeba ts'ebetso ea ho kopanya mali e sa tloaeleha, e ka lebisa ho thrombosis kapa mali, e leng se ka behang bophelo ba mokuli kotsing haholo.Tlhokomelo ea bongaka ea litekanyetso tsa PT le APTT e ka sebelisoa e le mokhoa oa ts'ebeliso ea litlhare tse ling tsa anticoagulant ts'ebetsong ea tleliniki.Haeba litekanyetso tse lekantsoeng li phahame haholo, ho bolela hore tekanyo ea lithethefatsi tsa anticoagulant e lokela ho fokotseha, ho seng joalo ho tsoa mali ho tla hlaha habonolo.

1. Nako ea Prothrombin (PT): Ke e 'ngoe ea matšoao a hlokolosi haholoanyane a tsamaiso ea mali ea motho.Ho bohlokoa haholo ho lelefatsa nako ea metsotsoana e fetang 3 ts'ebetsong ea bongaka, e ka bonts'ang hore na ts'ebetso ea exogenous coagulation e tloaelehile.Ho lelefatsa ka kakaretso ho bonoa ka congenital coagulation Ho haella ha Factor, ho thatafala ha sebete, ho hloleha ha sebete le mafu a mang.Ho phaella moo, tekanyo e feteletseng ea heparin le warfarin e ka boela ea baka PT e telele;

2. Activated partial thromboplastin time (APTT): Haholo-holo ke index e bonts'ang ts'ebetso ea endogenous blood coagulation ts'ebetsong ea bongaka.Katoloso e kholo ea APTT e bonoa haholo-holo ka khaello ea congenital kapa e fumanoeng ea coagulation factor, joalo ka hemophilia le systemic lupus erythematosus.Haeba tekanyetso ea lithethefatsi tsa anticoagulant e sebelisoang ka lebaka la thrombosis e sa tloaeleha, e tla baka keketseho e kholo ea APTT.Haeba boleng bo lekantsoeng bo le tlase, nahana hore mokuli o boemong ba hypercoagulable, joalo ka thrombosis ea methapo e tebileng.

Haeba u batla ho tseba hore na PT le APTT ea hau li tloaelehile, u hloka ho hlakisa mofuta oa tsona o tloaelehileng.Mokhoa o tloaelehileng oa PT ke metsotsoana e 11-14, 'me sebaka se tloaelehileng sa APTT ke metsotsoana e 27-45.Ho lelefatsa PT ho feta metsotsoana ea 3 ho na le bohlokoa bo boholo ba kliniki, 'me ho lelefatsa APTT ka metsotsoana e fetang 10 ho na le bohlokoa bo matla ba kliniki.