Mekhoa ea phekolo ea thrombosis haholo-holo e kenyelletsa phekolo ea lithethefatsi le phekolo ea ho buuoa.Phekolo ea lithethefatsi e arotsoe ka lithethefatsi tsa anticoagulant, lithethefatsi tsa antiplatelet, le lithethefatsi tsa thrombolytic ho latela mokhoa oa ts'ebetso.E qhala thrombus.Bakuli ba bang ba fihlelang matšoao le bona ba ka phekoloa ka ho buuoa.
1. Kalafo ea lithethefatsi:
1) Li-anticoagulants: Heparin, warfarin le li-anticoagulants tse ncha tsa molomo li sebelisoa hangata.Heparin e na le phello e matla ea anticoagulant ka har'a vivo le in vitro, e ka thibelang ka nepo thrombosis ea methapo e tebileng le embolism ea pulmonary.Hangata e sebelisoa ho phekola acute myocardial infarction le venous thromboembolism.Hoa lokela ho hlokomeloa hore heparin e ka aroloa ka heparin e sa tsitsang le heparin e tlaase ea boima ba molek'hule, ea ho qetela Haholo-holo ka ente ea subcutaneous.Warfarin e ka thibela lintlha tsa coagulation tse itšetlehileng ka vithamine K hore li se ke tsa etsoa.Ke anticoagulant ea mofuta oa dicoumarin e bohareng.E sebelisoa haholo-holo bakeng sa bakuli ka mor'a ho nkeloa sebaka ke valve ea pelo ea maiketsetso, kotsi e kholo ea atrial fibrillation le bakuli ba thromboembolism.Ho tsoa mali le litlamorao tse ling tse mpe li hloka hore ho be le leihlo le haufi la ho sebetsa ha coagulation nakong ea kalafo.Li-anticoagulants tse ncha tsa molomo li batla li bolokehile ebile li sebetsa hantle lilemong tsa morao tjena, ho kenyelletsa le lithethefatsi tsa saban le dabigatran etexilate;
2) Lithethefatsi tsa antiplatelet: ho kenyelletsa aspirin, clopidogrel, abciximab, joalo-joalo, li ka thibela ho kopana ha liplatelete, ka hona ho thibela sebopeho sa thrombus.Ka lefu le matla la "coronary syndrome", "coronary artery balloon dilatation", le maemo a phahameng a thrombotic joalo ka ho kenngoa ha stent, aspirin le clopidogrel hangata li sebelisoa hammoho;
3) Lithethefatsi tsa Thrombolytic: ho kenyelletsa streptokinase, urokinase le li-tissue plasminogen activator, joalo-joalo, tse ka khothalletsang thrombolysis le ho ntlafatsa matšoao a bakuli.
2. Kalafo ea ho buuoa:
Ho kenyelletsa thrombectomy, catheter thrombolysis, ultrasonic ablation, le mechanical thrombus aspiration, hoa hlokahala ho utloisisa ka tieo matšoao le li-contraindications tsa ho buuoa.Tleliniki, ho lumeloa ka kakaretso hore bakuli ba thrombus bobeli bakoang ke khale thrombus, coagulation ho se sebetse, le lihlahala tse kotsi ha ba a loketse bakeng sa phekolo ea ho buoa, 'me ba hloka ho phekoloa ho ea ka tsoelo-pele ea boemo ba mokuli le tlas'a tataiso ea ngaka.