Coagulation disgnostic haholo-holo e kenyelletsa plasma prothrombin time (PT), activated partial prothrombin time (APTT), fibrinogen (FIB), thrombin time (TT), D-dimer (DD), international standardization Ratio (INR).
PT: Haholo-holo e bontša boemo ba tsamaiso ea extrinsic coagulation, eo hangata INR e sebelisetsoang ho shebella li-anticoagulants tsa molomo.Ho lelefatsa ho bonoa ka congenital coagulation factor ⅡⅤⅦⅩ khaello le khaello ea fibrinogen, 'me khaello e fumanoeng ea coagulation factor e bonoa haholo-holo ka khaello ea vithamine K, lefu le matla la sebete, hyperfibrinolysis, DIC, anticoagulants ea molomo, joalo-joalo;khutsufatso e bonoa mali hypercoagulable boemo le lefu la thrombosis, joalo-joalo.
APTT: E bonts'a haholo boemo ba "endogenous coagulation system", 'me hangata e sebelisoa ho lekola litekanyetso tsa heparin.Ho eketseha ha plasma factor VIII, factor IX le factor XI e fokotsehile maemo: joalo ka hemophilia A, hemophilia B le ho haella ha factor XI;e fokotsehile ka boemo ba hypercoagulable: joalo ka ho kena ha lintho tsa procoagulant maling le ts'ebetso e eketsehileng ea lintlha tsa coagulation, joalo-joalo.
FIB: haholo-holo e bonahatsa litaba tsa fibrinogen.Keketseho ea acute myocardial infarction le ho fokotseha ha DIC consumptive hypocoagulable dissolution period, primary fibrinolysis, hepatitis e matla, le cirrhosis ea sebete.
TT: Haholo-holo e bonahatsa nako eo fibrinogen e fetoloang ho fibrin.Keketseho e ile ea bonoa sethaleng sa hyperfibrinolysis sa DIC, se nang le fibrinogenemia e tlaase (ha ho), hemoglobinemia e sa tloaelehang, le ho eketseha ha lihlahisoa tsa ho senyeha ha fibrin (fibrinogen) (FDP) maling;ho fokotseha ho ne ho se na bohlokoa ba kliniki.
INR: The International Normalized Ratio (INR) e baloa ho tloha ka nako ea prothrombin (PT) le International Sensitivity Index (ISI) ea reagent ea assay.Tšebeliso ea INR e etsa hore PT e lekanyetsoe ka lilaboratori tse fapaneng le li-reagents tse fapaneng tse bapisoang, tse thusang ho kopanya litekanyetso tsa lithethefatsi.
Bohlokoa bo ka sehloohong ba tlhahlobo ea mali ea coagulation bakeng sa bakuli ke ho hlahloba hore na ho na le bothata leha e le bofe ka mali, e le hore lingaka li ka utloisisa boemo ba mokuli ka nako, ’me ho loketse hore lingaka li noe meriana le phekolo e nepahetseng.Letsatsi le molemo ka ho fetisisa la hore mokuli a etse liteko tse hlano tsa coagulation ke ka mpeng e se nang letho, e le hore liphello tsa tlhahlobo li tla nepahala haholoanyane.Ka mor'a tlhahlobo, mokuli o lokela ho bontša liphetho tsa liteko ho ngaka ho fumana mathata a mali le ho thibela likotsi tse ngata.