Bothata ba ho koala mali bo beha bophelo kotsing, hobane mathata a coagulation a bakoa ke mabaka a sa tšoaneng a bakang bothata ba 'mele oa motho oa coagulation.Ka mor'a ho se sebetse ha coagulation, letoto la matšoao a mali a tla hlaha.Haeba hemorrhage e matla ea intracranial e etsahala, ho na le kotsi e kholo ea bophelo.Hobane ho na le mafu a mangata a bakoang ke ho se sebetse ha coagulation, kliniki e atileng haholo ke hemophilia A, haemophilia B, vascular hemophilia, khaello ea vithamine K, ho hasanya methapo ea mali ka vithamine Mafu ana a ka baka mafu a sa sebetseng a coagulation.Haeba e le mokuli ea nang le haemophilia e matla haholo, ho na le tšekamelo ea ho tsoa mali ka bohona.Ka mor'a ts'oaetso e fokolang, ho bonolo ho tsoa mali.Haeba bakuli ba nang le haemophilia e matla ea haemophilia A ba tšoeroe ke ho sithabela maikutlo, ho bonolo ho baka mali a mangata a craniocerebral, a behang bophelo ba mokuli kotsing.Ho phaella moo, e matla ka hare methapo ea mali coagulation, ka lebaka la ho tshebediso le coagulation ho se sebetse lintho tse fapa-fapaneng coagulation, le tsekamelo ea ho tsoa mali a mangata, e isang lefung la pele la mokuli.