Mathata a coagulation a beha bophelo kotsing, hobane mathata a coagulation a bakoa ke mabaka a sa tšoaneng a etsang hore mosebetsi oa 'mele oa motho o fokotsehe.Ka mor'a ho se sebetse ha coagulation, 'mele oa motho o tla hlaha letoto la matšoao a tsoang mali.Haeba ho hlaha mali a mangata haholo ka har'a cranial, ho beha bophelo kotsing.Hobane ho se sebetse ha coagulation ho ka bakoa ke mafu a fapaneng, khaello ea vithamine K e atileng haholo, ho ata ha methapo ea methapo, lefu le matla la sebete, lefu la hemophilia a, hemophilia b, lefu la von Willebrand, joalo-joalo.

Haeba e le mokuli ea nang le haemophilia e matla haholo, o na le tšekamelo e totobetseng ea ho tsoa mali, 'me ho bonolo ho etsa hore a tsoe mali ka mor'a kotsi e fokolang.Haeba mokuli ea nang le haemophilia e matla ea haemophilia A a e-ba le ts'oaetso, ho bonolo ho baka ho tsoa mali ho matla bokong, e leng ho behang bophelo ba mokuli kotsing.Ntle le moo, ho phatloha ho matla ha methapo ea methapo ho boetse ho na le tšekamelo ea ho tsoa mali haholo ka lebaka la tšebeliso ea lintlha tse fapaneng tsa coagulation le ho se sebetse ha coagulation, ho lebisang lefung la pele la bakuli.