Blood coagulation ka kakaretso ha e teng hore na e ntle kapa e mpe.Ho kopana ha mali ho na le nako e tloaelehileng.Haeba e potlakile haholo kapa e lieha haholo, e tla ba kotsi 'meleng oa motho.

Ho kopana ha mali ho tla ba ka har'a mefuta e itseng e tloaelehileng, e le hore e se ke ea baka ho tsoa mali le ho thehoa ha thrombus 'meleng oa motho.Haeba coagulation ea mali e potlakile haholo, hangata e bontša hore 'mele oa motho o boemong ba hypercoagulable,' me mafu a pelo le cerebrovascular a atisa ho etsahala, a kang cerebral infarction le Myocardial infarction, thrombosis e tlaase ea venous le mafu a mang.Haeba mali a mokuli a hoama butle haholo, ho ka etsahala hore a be le bothata ba ho hoama, a tloaetse ho tsoa mali, a kang haemophilia, ’me maemong a matla haholo, a tla siea ho holofala ha manonyeletso le lintho tse ling tse mpe.

Ts'ebetso e ntle ea thrombin e bontša hore liplatelete li sebetsa hantle ebile li phetse hantle.Coagulation e bolela mokhoa oa ho fetoha ha mali ho tloha boemong bo phallang ho ea boemong ba gel, 'me moelelo oa eona ke mokhoa oa ho fetolela fibrinogen e qhibilihang hore e be insoluble fibrinogen ka plasma.Ka kutloisiso e moqotetsane, ha methapo ea mali e senyehile, 'mele o hlahisa lintho tsa coagulation, tse kenngoeng tšebetsong ho hlahisa thrombin, eo qetellong e fetolang fibrinogen hore e be fibrin, kahoo e khothalletsa ho kopana ha mali.Coagulation hangata e kenyelletsa ts'ebetso ea platelet.

Ho ahlola hore na coagulation e ntle kapa che ke haholo-holo ka ho tsoa mali le liteko tsa laboratori.Coagulation dysfunction e bolela mathata a coagulation factor, ho fokotseha ha bongata kapa ho sebetsa ka mokhoa o sa tloaelehang, le letoto la matšoao a ho tsoa mali.Ho tsoa mali ho itlelang feela ho ka hlaha, 'me letlalong le lera la mucous le ka bonoa letlalong le lera la mamina.Ka mor'a ho tsieleha kapa ho buuoa, ho tsoa mali hoa eketseha 'me nako ea ho tsoa mali e ka ba nako e telele.Ka ho lemoha nako ea prothrombin, nako ea prothrombin e sa sebetseng ka mokhoa o itseng le lintho tse ling, ho fumanoa hore ts'ebetso ea coagulation ha e ntle, 'me sesosa sa ho hlahlojoa se lokela ho hlakisoa.