Li-index tsa tlhahlobo ea ts'ebetso ea coagulation li kenyelletsa nako ea prothrombin (PT), nako e kentsoeng ea karolo ea thromboplastin (APTT), nako ea thrombin (TT), fibrinogen (FIB), nako ea ho koala (CT) le International normalized ratio (INR), joalo-joalo, lintho tse 'maloa li ka ba teng. khethiloe ho etsa sephutheloana, se bitsoang coagulation X ntho.Ka lebaka la mekhoa e fapaneng ea ho lemoha e sebelisoang ke lipetlele tse fapaneng, libaka tsa litšupiso le tsona li fapane.

Nako ea PT-prothrombin

PT e bolela ho eketsa ntho ea li-tissue (TF kapa tissue thromboplastin) le Ca2 + ho plasma ho qala mokhoa oa ho tsoa ka ntle oa coagulation le ho boloka nako ea ho kopana ha plasma.PT ke e 'ngoe ea liteko tse sebelisoang ka ho fetisisa tsa ho hlahloba lits'ebetso tsa bongaka ho hlahloba mosebetsi oa extrinsic coagulation pathway.Boleng bo tloaelehileng ba litšupiso ke metsotsoana e 10 ho isa ho e 14.

APTT - e kentsoeng nako ea karolo ea thromboplastin

APTT ke ho eketsa XII factor activator, Ca2+, phospholipid ho plasma ho qala tsela ea plasma endogenous coagulation, le ho shebella nako ea plasma coagulation.APTT hape ke e 'ngoe ea liteko tsa tlhahlobo tse sebelisoang hangata litloaelong tsa bongaka ho lekola tšebetso ea tsela ea intrinsic coagulation.Boleng bo tloaelehileng ba referense ke metsotsoana e 32 ho isa ho e 43.

INR - Karolelano e Tloaelehileng ea Machaba

INR ke matla a ISI a karo-karolelano ea PT ea mokuli ea lekiloeng ho PT ea taolo e tloaelehileng (ISI ke index ea machaba ea kutloisiso, 'me reagent e lekanngoa ke moetsi ha e tloha fekthering).Plasma e tšoanang e ile ea lekoa ka li-reagents tse fapaneng tsa ISI lilaboratoring tse fapaneng, 'me liphetho tsa boleng ba PT li ne li fapane haholo, empa litekanyetso tse lekantsoeng tsa INR li ne li tšoana, tse ileng tsa etsa hore liphetho li bapisoe.Boleng bo tloaelehileng ba litšupiso ke 0.9 ho isa ho 1.1.

Nako ea TT-thrombin

TT ke tlatsetso ea thrombin e tloaelehileng ho plasma ho lemoha mohato oa boraro oa ts'ebetso ea coagulation, e bontšang boemo ba fibrinogen ka plasma le bongata ba lintho tse kang heparin ka plasma.Boleng bo tloaelehileng ba litšupiso ke metsotsoana e 16 ho isa ho e 18.

FIB-fibrinogen

FIB ke ho eketsa palo e itseng ea thrombin ho plasma e lekiloeng ho fetola fibrinogen ka plasma ho fibrin, le ho bala litaba tsa fibrinogen ka molao-motheo oa turbidimetric.Boleng bo tloaelehileng ba litšupiso ke 2 ho isa ho 4 g/L.

Sehlahisoa sa ho senyeha ha FDP-plasma fibrin

FDP ke lentsoe le akaretsang bakeng sa lihlahisoa tsa ho senyeha tse hlahisoang ka mor'a hore fibrin kapa fibrinogen e senyehe tlas'a ketso ea plasmin e hlahisoang nakong ea hyperfibrinolysis.Boleng bo tloaelehileng ba litšupiso ke 1 ho isa ho 5 mg/L.

CT-coagulation nako

CT e bolela nako eo ka eona mali a tlohang methapong ea mali 'me a hoama ka har'a vitro.Haholo-holo e etsa qeto ea hore na lintlha tse fapa-fapaneng tsa coagulation ka har'a intrinsic coagulation pathway li haella, hore na mosebetsi oa tsona ke o tloaelehileng, kapa hore na ho na le keketseho ea lintho tsa anticoagulant.