Thrombosis hangata e na le maemo a latelang a mararo:

1. Leqeba la intima la pelo le methapo ea mali

Kamano ea methapo e tloaelehileng ea pelo le ea mali e tiile ebile e boreleli, 'me lisele tsa endothelial tse tiileng li ka thibela ho khomarela ha platelet le anticoagulation.Ha lera le ka hare le senyehile, tsamaiso ea coagulation e ka etsoa ka litsela tse ngata.

Intima ea pele e senyehileng e lokolla li-tissue coagulation factor (coagulation factor III), e kenyang ts'ebetso ea "extrinsic coagulation system".
Ea bobeli, ka mor'a hore intima e senyehe, lisele tsa endothelial li senyeha, li-necrosis, le ho tšolloa, li pepesa likhoele tsa collagen tlas'a endothelium, kahoo li kenya tšebetsong "coagulation factor XII" ea "endogenous coagulation system" le ho qala tsamaiso ea endogenous coagulation.Ho phaella moo, intima e senyehileng e fetoha e thata, e leng se loketseng ho kenngoa ha platelet le ho khomarela.Ka mor'a hore li-platelet tse khomaretsoeng li phatlohe, mefuta e sa tšoaneng ea li-platelet e lokolloa, 'me mokhoa oohle oa coagulation oa sebetsa, o etsa hore mali a kopane le ho etsa thrombus.
Lintho tse fapa-fapaneng tsa 'mele, tsa lik'hemik'hale le tsa likokoana-hloko li ka baka tšenyo ea intima ea pelo, joalo ka endocarditis ho erysipelas ea likolobe, pulmonary vasculitis ka pneumonia ea bovine, equine parasitic arteritis, liente tse pheta-phetoang karolong e le' ngoe ea mothapo, Kotsi le ho phunya lebota la methapo ea mali. nakong ea ho buuoa.

2. Liphetoho tsa boemo ba phallo ea mali

Haholo-holo e bua ka phallo ea mali butle, sebopeho sa vortex le ho khaotsa ho phalla ha mali.
Tlas'a maemo a tloaelehileng, sekhahla sa phallo ea mali se potlakile, 'me lisele tse khubelu tsa mali, liplatelete le likarolo tse ling li lebisitsoe bohareng ba sejana sa mali, se bitsoang axial flow;ha lebelo la phallo ea mali le fokotseha, lisele tse khubelu tsa mali le liplatelete li tla phalla haufi le lerako la methapo ea mali, le bitsoang phallo ea lehlakore, e leng ho eketsang thrombosis.kotsi e hlahang.
Phallo ea mali e ea fokotseha, 'me lisele tsa endothelial li na le hypoxic e matla, e bakang ho senyeha le necrosis ea lisele tsa endothelial, tahlehelo ea mosebetsi oa tsona oa ho kopanya le ho lokolla lintho tsa anticoagulant, le ho pepeseha ha collagen, e etsang hore tsamaiso ea coagulation e tsoele pele. thrombosis.
Ho phalla ha mali butle ho ka boela ha etsa hore thrombus e entsoeng e be bonolo ho e lokisa leboteng la methapo ea mali 'me e tsoele pele ho eketseha.

Ka hona, thrombus hangata e hlaha methapong e nang le phallo e liehang ea mali le e atisang ho ba le maqhubu a eddy (li-valve tsa venous).Phallo ea mali ea aortic e potlakile, 'me thrombus e bonoa seoelo.Ho ea ka lipalo-palo, ketsahalo ea venous thrombosis ke makhetlo a 4 ho feta ea arterial thrombosis, 'me venous thrombosis hangata e hlaha ka ho hloleha ha pelo, ka mor'a ho buuoa kapa liphoofolong tse kulang tse robetseng sehlaheng nako e telele.
Ka hona, ho bohlokoa haholo ho thusa liphoofolo tse kulang tse 'nileng tsa robala nako e telele le ka mor'a ho buuoa ho etsa mesebetsi e nepahetseng ho thibela thrombosis.
3. Liphetoho tsa thepa ea mali.

Haholo-holo e bua ka ho eketseha ha mali coagulation.Tse kang ho chesa haholo, ho felloa ke metsi 'meleng, joalo-joalo ho tsepamisa mohopolo maling, ho sithabela ho matla, postpartum, le tahlehelo e matla ea mali ka mor'a ts'ebetso e kholo e ka eketsang palo ea liplatelete maling, ho eketsa viscosity ea mali, le ho eketsa litaba tsa fibrinogen, thrombin le lintlha tse ling tsa coagulation. ka plasma Keketseho.Lintho tsena li ka baka thrombosis.