Hoa khoneha ho tseba hore na mokuli o na le ts'ebetso e sa tloaelehang ea coagulation pele ho buuoa, ka katleho ho thibela maemo a sa lebelloang a kang ho tsoa mali a sa khaotseng nakong le ka mor'a ho buuoa, e le hore a fumane phello e ntle ka ho fetisisa ea ho buuoa.
Mosebetsi oa 'mele oa hemostatic o finyelloa ke ketso e kopanetsoeng ea liplatelete, tsamaiso ea coagulation, fibrinolytic system le vascular endothelial system.Nakong e fetileng, re ne re sebelisa nako ea ho tsoa ha mali e le teko ea ho hlahloba bokooa ba ts'ebetso ea hemostatic, empa ka lebaka la maemo a eona a tlaase, kutloisiso e fokolang, le ho sitoa ho bonahatsa litaba le mosebetsi oa coagulation factor, e nkeloe sebaka ke liteko tsa coagulation function.Liteko tsa ts'ebetso ea coagulation haholo-holo li kenyelletsa nako ea plasma prothrombin (PT) le ts'ebetso ea PT e baloang ho tloha PT, international normalized ratio (INR), fibrinogen (FIB), activated partial thromboplastin time (APTT) le plasma thrombin time (TT).
PT haholo-holo e bonahatsa mosebetsi oa "extrinsic coagulation system".PT e telele e bonoa haholo-holo ka congenital coagulation factor II, V, VII, le X phokotso, khaello ea fibrinogen, khaello e fumanoeng ea coagulation factor (DIC, primary hyperfibrinolysis, obstructive jaundice, khaello ea vithamine K, le lintho tsa anticoagulant maling. Haholo-holo e bonoa ka congenital coagulation factor V keketseho, DIC ea pele, mafu a thrombotic, lithibela-pelehi tsa molomo, joalo-joalo; monitor PT e ka sebelisoa e le tlhahlobo ea litlhare tse thibelang mali ho tsoa molomong.
APTT ke tlhahlobo e tšepahalang ka ho fetisisa ea tlhahlobo bakeng sa khaello ea endogenous coagulation factor.APTT e telele e bonoa haholo-holo ho haemophilia, DIC, lefu la sebete le tšelo e khōlō ea mali a banka.APTT e khutsufalitsoeng e bonoa haholo ho DIC, prothrombotic state, le mafu a thrombotic.APTT e ka sebelisoa e le sesupo sa ho beha leihlo bakeng sa kalafo ea heparin.
Ho lelefatsa ha TT ho bonoa ka hypofibrinogenemia le dysfibrinogenemia, ho eketseha ha FDP maling (DIC), le ho ba teng ha heparin le lintho tsa heparinoid maling (mohlala, nakong ea phekolo ea heparin, SLE, lefu la sebete, joalo-joalo).
Ho kile ha e-ba le mokuli oa tšohanyetso ea ileng a fumana liteko tsa laboratori ea pele ho ts'ebetso, 'me liphello tsa tlhahlobo ea coagulation li ne li lelefalitsoe PT le APTT,' me DIC e ne e belaelloa ho mokuli.Tlas'a khothaletso ea laboratori, mokuli o ile a etsa letoto la liteko tsa DIC 'me liphetho li ne li le ntle.Ha ho matšoao a hlakileng a DIC.Haeba mokuli a se na tlhahlobo ea coagulation, le ho buuoa ka ho toba, liphello e tla ba tse kotsi.Mathata a joalo a mangata a ka fumanoa tekong ea ts'ebetso ea coagulation, e rekileng nako e eketsehileng bakeng sa ho lemoha le kalafo ea mafu.Teko ea letoto la coagulation ke teko ea bohlokoa ea laboratori bakeng sa ts'ebetso ea coagulation ea bakuli, e ka lemohang ts'ebetso e sa tloaelehang ea coagulation ho bakuli pele ho opereishene, 'me e lokela ho lebisoa tlhokomelo e lekaneng.
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