Hemostasis physiological waa mid ka mid ah hababka ilaalinta muhiimka ah ee jirka.Marka xididdada dhiigga ay dhaawacmaan, dhinaca kale, waxaa loo baahan yahay in la sameeyo fur hemostatic si degdeg ah si looga fogaado dhiig-baxa;Dhanka kale, waxaa lagama maarmaan ah in la xaddido jawaabta hemostatic ee qaybta dhaawaca ah iyo in la ilaaliyo xaaladda dareeraha ee dhiigga ee xididdada dhiigga ee nidaamka.Sidaa darteed, hemostasis physiological waa natiijada arrimo kala duwan iyo hababka isdhexgalka si loo ilaaliyo dheelitirka saxda ah.Caafimaad ahaan, irbado yaryar ayaa inta badan loo isticmaalaa in lagu dalooliyo xuubka dhegta ama faraha faraha si loo oggolaado in dhiiggu si dabiici ah u soo baxo, ka dibna lagu cabbiro muddada dhiig-baxa.Xilligan waxaa loo yaqaannaa waqtiga dhiig-baxa (waqtiga dhiig-baxa), dadka caadiga ahna kama badna 9 daqiiqo (habka qaab-dhismeedka).Dhererka wakhtiga dhiig-baxa wuxuu ka tarjumayaa xaaladda shaqada hemostatic physiological .Marka shaqada hemostatic physiological la daciifiyo, dhiigbaxa u janjeera inuu dhaco, iyo cudurada dhiigbaxa;halka firfircoonida xad dhaafka ah ee shaqada hemostatic physiological waxay keeni kartaa xinjirowga dhiigga.
Habka aasaasiga ah ee hemostasis physiological
Habka hemostasis physiological inta badan waxaa ka mid ah saddex hab: vasoconstriction, xinjirowga platelet iyo xinjirowga dhiigga.
1 Vasoconstriction Hemostasis Physiological Hemostasis marka hore waxaa lagu muujiyaa foosha xididdada dhiigga ee dhaawacan iyo xididdada yar yar ee u dhow, taas oo yaraynaysa socodka dhiigga deegaanka waxayna faa'iido u leedahay in la yareeyo ama laga hortago dhiig-baxa.Sababaha vasoconstriction waxaa ka mid ah saddexda dhinac ee soo socda:② Burbur ku yimaada darbiga xididada xididada ayaa sababa xanuunka myogenic vascular vascular;③ Platelets oo ku dheggan dhaawaca waxay sii daayaan 5-HT, TXA₂, iwm si ay u xaddidaan xididdada dhiigga.walxaha keena vasoconstriction.
2 Samaynta xinjirowga dhiigga ee xididdada dhiigga ka dib dhaawaca xididdada dhiigga, sababtoo ah soo-gaadhista kolajka subendothelial, qadar yar oo platelet ah ayaa ku dheggan kolajka subendothelial 1-2 ilbiriqsi gudahood, taas oo ah tallaabada ugu horreysa ee samaynta thrombus hemostatic.Iyada oo la adeegsanayo adhesion of platelets, goobta dhaawaca ayaa "la aqoonsan karaa", si furaha hemostatic si sax ah loo dhigo.Platelets-ku-xidhan waxay sii dhaqaajiyaan dariiqyada calaamadaynta platelet si ay u dhaqaajiyaan platelet oo ay u sii daayaan ADP iyo TXA₂ endogenous, taas oo markaa kicisa platelets kale ee dhiiga, qorta platelet badan si ay isugu dheggan yihiin oo ay keenaan isu-ururin aan laga noqon karin;Unugyada dhiigga cas ee dhaawaca ah ayaa sii daaya ADP iyo maxalliga thrombin ka dhasha habka xinjirowga ayaa ka dhigi kara platelets ee ku qulqulaya nabarka si joogto ah ugu dheggan oo ku soo ururaan platelets kuwaas oo lagu dhejiyay kolajka subendothelial, ugu dambeyntiina waxay sameeyaan fiilo hemostatic platelet. xidho dhaawaca oo gaadha hemostasis horudhac ah, oo sidoo kale loo yaqaano hemostasis aasaasiga ah (irsthemostasis).Hemostasis aasaasiga ah wuxuu inta badan ku xiran yahay vasoconstriction iyo samaynta furaha hemostatic platelet.Intaa waxaa dheer, hoos u dhigista PGI₂ iyo wax soo saarka NO ee endothelium xididada xididada ah ee dhaawacan ayaa sidoo kale faa'iido u leh isku-darka platelets.
3 xinjirowga dhiigga Xididdada dhiigga ee dhaawacan ayaa sidoo kale hawlgelin kara nidaamka xinjirowga dhiigga, iyo xinjirowga dhiigga maxalliga ah si degdeg ah ayuu u dhacaa, si fibrinogen-ka milmaya ee Plasma loo beddelo fibrin aan la milmi karin, oo la isku xidho shabakad si ay u xoojiso xuubka hemostatic, kaas oo loo yaqaanno secondary. hemostasis (hemostasis labaad) hemostasis) (Jaantuska 3-6).Ugu dambayntii, unugyada fibroeska ah ee deegaanka ayaa fidaya oo u koraa xinjiro dhiig si loo gaaro hemostasis joogto ah.
Hemostasis Physiological Hemostasis waxa loo qaybiyaa saddex hab: vasoconstriction, platelet thrombus formation, iyo xinjirowga dhiigga, laakiin saddexdan hab ayaa si isdaba-joog ah u dhaca oo midba midka kale isku dhejiyaa, waxayna si dhow isugu xiran yihiin midba midka kale.Adhesion platelet waa sahlan tahay in la gaaro kaliya marka socodka dhiigga uu hoos u dhigo vasoconstriction;S-HT iyo TXA2 la sii daayo ka dib firfircoonida platelet waxay kor u qaadi karaan vasoconstriction.Platelets-ka firfircooni waxay bixiyaan korka phospholipid ee kicinta arrimaha xinjirowga dhiigga inta lagu jiro xinjirowga dhiigga.Waxaa jira arrimo badan oo xinjirowga lidka ku ah oo ku xiran dusha sare ee platelet, platelets waxay sidoo kale sii deyn karaan arrimaha xinjirowga sida fibrinogen, taas oo si weyn u soo dedejisa habka xinjirowga.thrombin-ka la soo saaro inta lagu jiro xinjirowga dhiigga wuxuu xoojin karaa firfircoonida platelet.Intaa waxaa dheer, isku ururinta xinjirowga dhiigga ee xinjirowga dhiigga waxay keeni kartaa in xinjirowga dhiigga uu dib u gurto oo uu tuujiyo serumka ku jira, taasoo ka dhigaysa xinjirowga dhiigga mid adag oo si adag u xira furitaanka xididdada dhiigga.Sidaa darteed, saddexda hab ee hemostasis physiological waxay kor u qaadaan midba midka kale, si dhiig-baxa physiological hemostasis loo fuliyo waqti ku habboon oo degdeg ah.Sababtoo ah platelets waxay si dhow ula xiriiraan saddexda xiriiriye ee habka hemostasis physiological, platelets waxay door aad muhiim ah ka ciyaaraan habka physiological hemostasis.Wakhtiga dhiig-baxa waa la dheereeyaa marka platelets ay yaraato ama shaqada ay yaraato.