Waqtiga Prothrombin (PT) waa tilmaame aad muhiim u ah oo ka tarjumaya shaqada beerka, shaqada kaydka, darnaanta cudurka iyo saadaalinta.Waqtigan xaadirka ah, ogaanshaha kiliinikada ee qodobbada xinjirowga ayaa noqday mid dhab ah, waxayna bixin doontaa macluumaad hore oo sax ah oo ka badan PT marka loo eego xaaladda cudurka beerka.
Codsiga kiliinikada ee PT ee cudurka beerka:
Shaybaarku wuxuu PT u sheegaa afar siyaabood: Boqolkiiba waxqabadka prothrombintime PTA (saamiga prothrombin waqtiga PTR) iyo saamiga caadiga ah ee caalamiga ah INR.Afarta foom waxay leeyihiin qiimeyaal codsi caafimaad oo kala duwan.
Qiimaha codsiga ee PT ee cudurka beerka: PT inta badan waxaa lagu go'aamiyaa heerka xinjirowga dhiigga IIvX ee beerku sameeyay, doorkeeda cudurka beerka ayaa si gaar ah muhiim u ah.Heerka aan caadiga ahayn ee PT ee cagaarshow ba'an wuxuu ahaa 10% -15%, cagaarshow dabadheeraad ah wuxuu ahaa 15% -51%, cirrhosis wuxuu ahaa 71%, cagaarshow daran wuxuu ahaa 90%.Marka la eego shuruudaha ogaanshaha cagaarshowga fayraska ee 2000, PTA waa mid ka mid ah tilmaamayaasha heerka caafimaad ee bukaanada qaba cagaarshowga fayraska.Bukaanka cagaarshowga fayraska ee raaga ee leh PTA fudud>70%, dhexdhexaad ah 70%-60%, daran 60%-40%;cirrhosis oo leh heerka magdhow PTA>60% heerka dhimis PTA <60%;Cagaarshowga daran ee PTA <40%" Marka la eego kala-soocidda Child-Pugh, 1 dhibcood oo loogu talagalay kordhinta PT ee 1 ~ 4s, 2 dhibcood 4 ~ 6s, 3 dhibcood > 6s, oo ay weheliso 4 tilmaamayaal kale (albumin, bilirubin, ascites, encephalopathy ), shaqada beerka ee bukaanada qaba cudurka beerka Kaydadka waxaa loo qaybiyaa darajooyinka ABC; Dhibcaha MELD (Modelfor end-stageliver disease), kaas oo go'aaminaya darnaanta cudurka bukaanada qaba cudurka beerka ee marxaladda dhamaadka iyo isku xigxiga beerka beerka, formula waa .8xloge[bilirubin(mg/dl)+11.2xloge(INR)+9.6xloge[creatinine (mg/dl]+6.4x (sababta: biliary ama khamriga 0; kale 1), INR waa mid ka mid ah 3 tilmaamayaasha.
Shuruudaha ogaanshaha DIC ee cudurka beerka waxaa ka mid ah: Kordhinta PT in ka badan 5s ama qayb firfircoon oo thromboplastin ah (APTT) in ka badan 10s, factor VIII dhaqdhaqaaqa <50% (loo baahan yahay);Tirada PT iyo platelet-ka ayaa inta badan loo isticmaalaa si loo qiimeeyo biopsy beerka iyo qalliinka Dhiig-baxa bukaannada, sida platelets <50x10°/L, iyo PT-dheeraynta oo aad uga badan inta caadiga ah ee 4s ayaa liddi ku ah ka-qaadista beerka iyo qalliinka oo ay ku jiraan beerka beddelka.Waxaa la arki karaa in PT ay door muhiim ah ka ciyaarto ogaanshaha iyo daaweynta bukaanka qaba cudurka beerka.