Thrombin nguva (TT) uye prothrombin nguva (PT) inowanzoshandiswa coagulation basa rekuona zviratidzo, musiyano pakati pezviviri zviri pakuona zvakasiyana-siyana coagulation zvinhu.

Thrombin nguva (TT) chiratidzo chenguva inodiwa kuona kutendeuka kweplasma prothrombin mu thrombin.Inonyanya kushandiswa kuongorora mamiriro ekuita kwefibrinogen uye coagulation factor I, II, V, VIII, X uye XIII muplasma.Munguva yekuongorora, imwe chiyero chetishu prothrombin uye calcium ions inowedzerwa kuti ishandure prothrombin muplasma mu thrombin, uye nguva yekushandura inoyerwa, iyo inokosha yeTT.

Prothrombin nguva (PT) indekisi yekuona kushanda kweropa coagulation zvinhu kunze kweropa coagulation system.Munguva yekuongorora, imwe chiyero che coagulation factor composition (yakadai se coagulation factor II, V, VII, X uye fibrinogen) inowedzerwa kuti iite coagulation system, uye nguva yekugadzira clot inoyerwa, iyo ndiyo PT kukosha.Kukosha kwePT kunoratidza mamiriro ekuita coagulation factor kunze kweiyo coagulation system.

Izvo zvinofanira kuonekwa kuti zvose TT uye PT maitiro anowanzoshandiswa zviratidzo zvekuyera coagulation basa, asi izvo zviviri hazvigoni kutsiva mumwe nemumwe, uye zviratidzo zvakakodzera zvekuona zvinofanira kusarudzwa maererano nemamiriro chaiwo.Panguva imwecheteyo, zvinofanirwa kucherechedzwa kuti kusiyana kwemaitiro ekuona uye reagents kunogona kukanganisa kurongeka kwemhedzisiro, uye kutarisisa kunofanirwa kubhadharwa kune yakajairika maitiro mumakiriniki maitiro.