Thrombin inogona kukurudzira kubatana kweropa, kuita basa mukumisa kubuda ropa, uye zvakare inogona kukurudzira kuporeswa kwemaronda uye kugadzirisa matishu.

Thrombin chinhu chakakosha enzyme mukuita kweropa coagulation, uye iro enzyme yakakosha yakatanga kushandurwa kuita fibrin mufibrin.Kana tsinga dzeropa dzakuvadzwa, glycrase inogadzirwa pasi pechiito cheplatelet uye vascular endothelial masero, kukurudzira platelet agglomeration uye thrombosis, nokudaro kumisa hemostasis.Pamusoro pezvo, kurongeka kunogonawo kukurudzira kuporeswa kwemaronda uye kugadzirisa matishu, inova chinhu chakakosha enzyme mukugadzirisa matishu.

Izvo zvinofanirwa kucherechedzwa kuti yakawandisa activation ye thrombin inogonawo kukonzera matambudziko akadai se thrombosis uye chirwere chemoyo.Naizvozvo, zvinodikanwa kunyatsotevera zano rechiremba uye chipimo chemishonga kana uchishandisa coordinase-inoenderana zvinodhaka kuti udzivise kuita kwakashata nemhedzisiro.

Basa re fibrinogen pakutanga raive mhedzisiro yekusimudzira platelet agglomeration muropa coagulation.Fibrinogen pakutanga yaive puroteni yakakosha mukuita kwekubatana.Basa rayo guru ndiro coagulation uye hemostasis, uye kubatanidzwa mukugadzirwa kweplatelet.Yakajairika kukosha kwefibrinogen ndeye 2-4g/L.Kukwidziridzwa kwekutanga kwefibrin kwakabatana zvakanyanya nekuitika kwezvirwere zvethrombotic.Kuwedzera kwekukwira kwefibrin kunogona kukonzerwa nehupenyu hwehupenyu, hwakadai sekunonoka kubata pamuviri uye zera, kana pathological zvinhu, zvakadai sehypertension, chirwere cheshuga, coronary atherosclerotic heart disease.

Chiyero chefibrin chakaderedzwa, chinogona kukonzerwa nezvirwere zvechiropa, senge cirrhosis uye acute hepatitis.Varwere vanofanira kuenda kuchipatara kunoongororwa nenguva uye kuvarapa vachitungamirirwa nachiremba.