Thrombosis inowanzokonzerwa nekukuvadzwa kwemasero emwoyo endothelial, chimiro chekuyerera kweropa, uye kuwedzera kweropa coagulation.

1. Cardiovascular endothelial cell injury: Vascular endothelial cell injury ndiyo inonyanya kukosha uye inowanzokonzera thrombus formation, iyo inowanzoonekwa mu rheumatic uye infective endocarditis, yakaoma atherosclerotic plaque ulcer, traumatic or inflammatory motion Venous injury site, etc. Mukuwedzera, mushure me hypoxia, kuvhunduka, sepsis uye bhakitiriya endotoxin inokonzeresa yakakura endothelial kukuvadzwa mumuviri wese, iyo collagen iri pasi pe endothelium inomutsa iyo coagulation process, zvichikonzera kuparadzira intravascular coagulation, uye thrombus mafomu mune microcirculation yemuviri wese.

2. Chimiro chisina kujairika chekuyerera kweropa: kunonyanya kureva kuderera kwekuyerera kweropa uye chizvarwa cheeddies mukuyerera kweropa, etc. The activated coagulation factors uye thrombin inosvika kuconcentration inodiwa kuti iite coagulation munzvimbo yemunharaunda, iyo inobatsira kuumbwa kwe thrombus.Pakati pavo, tsinga dzinowanzoita thrombus, iyo inowanzoonekwa kune varwere vane mwoyo kusakundikana, chirwere chisingaperi uye postoperative bed rest.Mukuwedzera, ropa rinoyerera mukati memwoyo uye tsinga inokurumidza, uye hazvisi nyore kuumba thrombus.Zvisinei, kana ropa richiyerera muatrium yekuruboshwe, aneurysm, kana bazi remudziyo weropa rinononoka uye eddy ikozvino inoitika panguva yemitral valve stenosis, inowanzoita thrombosis.

3. Kuwedzera kweropa coagulation: Kazhinji, kuwedzera kweplatelet uye coagulation zvinhu muropa, kana kuderera kwebasa re fibrinolytic system, kunotungamirira kune hypercoagulable state muropa, iyo inowanzoonekwa munhaka uye yakawana hypercoagulable states.

Mukuwedzera, kusadzoka kweropa revenous kunogona kukonzera.Zvinoenderana nekuongororwa kunoshanda kwechirwere chemunhu, kudzivirira kwesainzi uye kurapwa kunogona kuwanikwa kubatsira hutano kupora.