APTT ndicho chipfupiso cheChirungu chenguva yakagadziriswa prothrombin nguva.APTT bvunzo yekuongorora inoratidza endo native coagulation nzira.Yakareba APTT inoratidza kuti imwe ropa coagulation chinhu chinobatanidzwa munzira yemunhu endogenous coagulation nzira haishande.Mushure mekunge APTT yarebesa, murwere anenge aine zviratidzo zvekubuda ropa zviri pachena.Semuenzaniso, varwere vane hemophilia A, hemophilia B, uye von Willebrand chirwere vose vanenge vatora nguva yakareba APTT, uye murwere achange ane ecchymosis paganda uye mucous membranes, uye kubuda ropa kwetsandanyama., Kubuda ropa pamwe chete, hematoma, etc. Kunyanya kuvarwere vane hemophilia A, kukanganiswa kwemajoini uye muscle atrophy inowanzosiiwa mushure mokunge hematoma inobatwa nekuda kwe synovitis inokonzerwa neropa rekubatana, iro rinokanganisa zvakanyanya hutano.Uye zvakare, kuparadzira intravascular coagulation, chirwere chechiropa chakakomba uye zvimwe zvirwere zvinokonzeresa kurebesa kwakakosha kweAPTT, izvo zvinozokonzera kukuvadza kuri pachena kumuviri wemunhu.
Kukosha kwakanyanya kweApt kunoratidza kuti murwere anogona kutambura nekubuda ropa.Zvinetso zvinowanzoitika zvekubuda ropa zvinosanganisira congenital coagulation factor deficiency uye hemophilia.Chechipiri, inofungidzirwa kuti inokonzerwa nechirwere chechiropa kana obstructive jaundice kana thrombotic chirwere.Izvo hazvitaurwiwo kunze kwekuti zvinokonzerwa nekukanganiswa kwezvinhu zvezvinodhaka, zvakadai sekushandiswa kwenguva refu kwemishonga inorwisa anticoagulant.Clinically, iyo apt bvunzo inogona kushandiswa kutonga kana coagulation basa mumuviri wemurwere rakajairika.Kana iri nekuda kwechiitiko chinokonzerwa nehemophilia, zvinokurudzirwa kutevera mazano echiremba kuti arege kubuda ropa kana kushandisa prothrombin complex treatment.