Thrombosis maitiro, kusanganisira maviri maitiro:

1. Kunamatira uye kuunganidzwa kwemaplatelet muropa

Muchikamu chekutanga che thrombosis, maplatelet anoramba achidonha kubva kune axial kuyerera uye anonamatira pamusoro peiyo yakafumurwa collagen fibers pa intima yemidziyo yeropa yakakuvadzwa.Maplatelet anoitwa ne collagen uye anoburitsa zvinhu zvakaita seADP, thromboxane A2, 5-AT uye platelet factor IV., Zvinhu izvi zvine simba rakasimba reagglutinating maplatelet, kuitira kuti maplatelet ari muropa arambe achiungana munzvimbo kuti aite murwi weplatelet yakaita murwi., kutanga kwevenous thrombosis, musoro we thrombus.

Maplatelet anonamira pamusoro peiyo yakafumurwa collagen fibers pane intima yeropa yakakuvadzwa tsinga uye inogadziriswa kuti igadzire hillock-yakafanana platelet stack.Iyo hillock zvishoma nezvishoma inowedzera uye inosanganiswa ne leukocytes kuti iite white thrombus.Iine akawanda leukocytes akabatanidzwa pamusoro payo.Ropa rinoyerera zvishoma nezvishoma, iyo coagulation system inotangwa, uye huwandu hukuru hwefibrin hunoumba network, iyo inoteya mamwe masero matsvuku eropa uye chena masero eropa kuita musanganiswa thrombus.

2. Ropa coagulation

Mushure mokunge chena thrombus yakaumbwa, inobuda mu vascular lumen, zvichiita kuti ropa riyerere shure kwayo riderere uye rionekwe semhepo, uye murwi mutsva weplatelet unoumbwa pamhepo.Trabeculae, yakaumbwa sekorari, ine maleukocyte akawanda akabatanidzwa pamusoro pawo.

Kuyerera kweropa pakati petrabeculae zvishoma nezvishoma kunonoka, iyo coagulation system inoshandiswa, uye kusungirirwa kwenzvimbo yekubatanidza coagulation zvinhu uye maplatelet zvinhu zvinowedzera zvishoma nezvishoma, zvichiita uye kupindirana mune mesh structure pakati pe trabeculae.Muchena nemuchena, corrugated yakasanganiswa thrombus inoumba muviri we thrombus.

Iyo yakasanganiswa thrombus yakawedzera zvishoma nezvishoma uye yakatambanudzwa munzira yekuyerera kweropa, uye pakupedzisira yakavhara zvachose lumen yetsinga yeropa, zvichiita kuti kuyerera kweropa kumire.