D-Dimer sechiratidzo chekufungidzira kwezvirwere zvakasiyana-siyana:

Nekuda kwehukama hwepedyo pakati peiyo coagulation system uye kuzvimba, endothelial kukuvadzwa, uye zvimwe zvisiri thrombotic zvirwere senge hutachiona, kuvhiyiwa kana kukuvadzwa, kutadza kwemoyo, uye mamota akaipa, kuwedzera kweD-Dimer kunowanzoonekwa.Mukutsvakurudza, zvakaonekwa kuti zvinowanzoitika zvakashata kufungidzira kwezvirwere izvi zvichiri thrombosis, DIC, nezvimwewo. Zvizhinji zvezvipingamupinyi izvi ndizvo chaizvo zvirwere zvinowanzoitika kana kuti nyika dzinokonzera kukwirira kweD-Dimer.Saka D-Dimer inogona kushandiswa seyakafara uye inonzwisisika yekuongorora chiratidzo chezvirwere.

1.Kune varwere vekenza, zvidzidzo zvakawanda zvakawana kuti 1-3 gore rekupona kwechirwere chechirwere chechirwere chechirwere chepamusoro cheD-Dimer chakanyanya kuderera pane cheavo vane D-Dimer yakajairika.D-Dimer inogona kushandiswa sechiratidzo chekuongorora fungidziro yevanorwara bundu varwere.

2.Kune varwere veVTE, zvidzidzo zvakawanda zvakasimbisa kuti D-Dimer varwere vane hutano panguva yeanticoagulation vane 2-3 nguva yakawanda yehuwandu hwehutachiona hunotevera hunofananidzwa nevarwere vasina kunaka.Imwe meta-analysis yevatori vechikamu 1818 muzvidzidzo zve 7 yakaratidza kuti D-Dimer isina kujairika ndeimwe yeanonyanya kufanotaura nezve thrombotic kudzokorora muvarwere veVTE, uye D-Dimer yakaverengerwa mune akawanda VTE maitiro ekudzokorora njodzi yekufanotaura.

3.Kune varwere vane mechanical valve replacement (MHVR), tsvakurudzo yenguva refu yekutevera yevatori vechikamu 618 yakaratidza kuti varwere vane mazinga eD-Dimer asina kujairika munguva yewarfarin mushure meMHVR vaiva nengozi yezviitiko zvakashata pamusoro pe5 nguva dzakakwirira kudarika avo. ane mazinga akajairika.Multivariate correlation analysis yakasimbisa kuti D-Dimer mazinga aive akazvimiririra ekufanotaura kwethrombosis kana zviitiko zvemoyo panguva yeanticoagulation.

4.Kune varwere vane atrial fibrillation (AF), D-Dimer inogona kufanotaura zviitiko zve thrombotic uye zvemwoyo panguva yemuromo anticoagulation.Ongororo inotarisirwa yevarwere ve269 vane atrial fibrillation yakateverwa kweanenge makore maviri yakaratidza kuti panguva yemuromo anticoagulation, vangangoita 23% yevarwere vakasangana neiyo INR standard vakaratidza mazinga eD-Dimer asina kujairika, nepo varwere vane D-Dimer mazinga aive ne15.8 uye 7.64 nguva yakakwira njodzi yethrombotic uye inopindirana yemoyo yezviitiko zvichienzaniswa nevarwere vane yakajairika D-Dimer mazinga, zvichiteerana.
Kune idzi hosha chaidzo kana varwere, yakakwira kana kuramba yakanaka D-Dimer kazhinji inoratidza kusarongeka kana kuwedzera kwemamiriro acho.