Yakajairika Coagulation Mechanism muVanhu: Thrombosis


Munyori: Mutsivi   

Vanhu vazhinji vanofunga kuti kugwamba kweropa chinhu chakaipa.

Cerebral thrombosis uye myocardial infarction inogona kukonzera sitiroko, kuoma mitezo kana kufa kamwe kamwe mumunhu mupenyu.

Chokwadi?

Muchokwadi, thrombus ingori yakajairika nzira yekuvhara ropa yemuviri wemunhu.Kana pasina thrombus, vanhu vazhinji vanofa nekuda kwe "kurasikirwa kweropa rakawandisa".

Mumwe nemumwe wedu akakuvara uye kubuda ropa, sekunge kuchekwa kudiki pamuviri, izvo zvinozobuda ropa nekukurumidza.Asi muviri wemunhu uchazvidzivirira.Kuti udzivise kubuda ropa kusvika pakufa, ropa rinozobatana zvishoma nezvishoma panzvimbo yekubuda ropa, kureva kuti, ropa richagadzira thrombus mutsinga yeropa yakakuvadzwa.Nenzira iyi, hapasisina kubuda ropa.

Apo kubuda ropa kunomira, muviri wedu unopedza zvishoma nezvishoma thrombus, zvichiita kuti ropa ritenderere zvakare.

Iyo nzira inoburitsa thrombus inonzi coagulation system;iyo nzira inobvisa thrombus inonzi fibrinolytic system.Kamwe mudziyo weropa uchinge wakuvadzwa mumuviri wemunhu, iyo coagulation system inogadziriswa nekukurumidza kudzivirira kuramba kubuda ropa;kana thrombus ikaitika, iyo fibrinolytic system inobvisa thrombus ichagadziriswa kuti iparadze jira reropa.

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Iwo maviri masisitimu ane dynamically akaenzana, kuve nechokwadi kuti ropa haridhure kana kubuda ropa zvakanyanya.

Zvisinei, zvirwere zvakawanda zvinotungamirira kukushanda kusina kujairika kweiyo coagulation system, pamwe nekukuvadza kune intima yemudziyo weropa, uye stasis yeropa ichaita kuti fibrinolytic system inonoka kana kusakwana kunyungudutsa thrombus.
Semuenzaniso, mune acute myocardial infarction, kune thrombosis mumoyo tsinga dzeropa.Mamiriro etsinga eropa akashata kwazvo, kune kukuvara kwakasiyana-siyana kwe intima, uye kune stenosis, pamwe nekumira kwekuyerera kweropa, hapana nzira yekunyungudutsa thrombus, uye thrombus inongowedzera kukura uye kukura.

Semuenzaniso, muvanhu vakarara kwenguva yakareba, ropa remunharaunda rinoyerera mumakumbo rinononoka, intima yemidziyo yeropa inokuvadza, uye thrombus inoumbwa.Iyo thrombus icharamba ichinyungudika, asi kukurumidza kunyungudika hakuna kukurumidza zvakakwana, inogona kudonha, ichiyerera ichidzokera mutsinga yemapapu ichitevedza hurongwa hweropa, inonamira mutsinga yemapapu, uye kukonzera pulmonary embolism, inouraya zvakare.
Panguva ino, kuitira kuti kuve nechokwadi chekuchengetedzwa kwevarwere, zvakakosha kuita zvekugadzira thrombolysis uye kupinza mishonga inoshandiswa kukurudzira thrombolysis, yakadai se "urokinase".Nekudaro, thrombolysis inowanzoda kuitwa mukati menguva pfupi yethrombosis, senge mukati memaawa matanhatu.Kana ikatora nguva yakareba, haizonyungudika.Kana iwe ukawedzera kushandiswa kwemishonga inonzi thrombolytic panguva ino, inogona kukonzera kubuda ropa mune dzimwe nzvimbo dzomuviri.
Iyo thrombus haigone kunyungudika.Kana isina kuvharika zvachose, "stent" inogona kushandiswa "kudhonza" tsinga yeropa yakavharika kuitira kuti ropa rifambe zvakanaka.

Zvisinei, kana tsinga yeropa yakavharwa kwenguva yakareba, inokonzera ischemic necrosis yezvikamu zvakakosha zvenyama.Panguva ino, chete ne "kunzvenga" mimwe tsinga yeropa inogona kuunzwa "kudiridza" chidimbu ichi chenyama chakarasikirwa neropa.

Kubuda ropa uye coagulation, thrombosis uye thrombolysis, ndiyo yakapfava chiyero inochengetedza metabolic mabasa emuviri.Kwete izvozvo zvoga, kune zvakawanda zvine hungwaru zvikero mumuviri womunhu, zvakadai setsinga inonzwira tsitsi uye vagus nerve, kuchengetedza vanhu kufara pasina kunyanya kufara;insulin uye glucagon inogadzirisa shuga yeropa revanhu;calcitonin uye parathyroid hormone inoronga vanhu ropa calcium balance.

Kana chiyero chisina kuenzana, zvirwere zvakasiyana-siyana zvichaonekwa.Zvirwere zvakawanda zviri mumuviri wemunhu zvinonyanya kukonzerwa nekurasikirwa kwechiyero.