Kana kusashanda zvakanaka kwemurwere kunokonzera kubuda ropa, zvinogona kukonzerwa nekudzikira kwekuita basa rekuita coagulation.Coagulation factor yekuongorora inodiwa.Zviri pachena kuti kubuda ropa kunokonzerwa nekushaya coagulation zvinhu kana zvimwe anticoagulation zvinhu.Zvinoenderana nechikonzero, wedzera inoenderana coagulation zvinhu kana nyowani plasma.Kuvapo kwezvimwe zvinogwambisa zvinogona kubatsira kumisa kubuda ropa.Clinically, inogona kuonekwa kana iyo inowirirana coagulation zvinhu zvemukati uye extrinsic coagulation nzira dze coagulation basa yakaderedzwa kana kuti ine dysfunction, uye tarisa kana iyo abnormal coagulation function inokonzerwa nekushaikwa kwe coagulation zvinhu kana basa re coagulation zvinhu, kunyanya. kusanganisira zvinotevera mamiriro:

1. Abnormal endogenous coagulation pathway: Chinhu chikuru coagulation chinokanganisa endogenous coagulation nzira ndeye APTT.Kana APTT yakarebesa, zvinoreva kuti kune zvikonzero zvisina kujairika coagulation munzira inopera, senge factor 12, factor 9, factor 8, and common pathway 10. Kushaikwa kwechikafu kunogona kukonzera kubuda ropa muvarwere;

2. Nzira isina kujairika extrinsic coagulation nzira: kana PT yakarebesa, inogona kuonekwa kuti tissue factor, factor 5 and factor 10 in the common pathway may all be abnormal, ndiko kuti, kuderera kwenhamba kunotungamirira kwenguva yakareba coagulation uye kunokonzera kubuda ropa. mumurwere.