D-dimer chigadzirwa chekushatisa chefibrin, chinowanzo shandiswa mukuita coagulation basa bvunzo.Chiyero chayo chakajairika ndeye 0-0.5mg/L.Kuwedzera kweD-dimer kunogona kunge kwakabatana nemamiriro emuviri akadai sekuzvitakura, kana Iyo yakabatana neiyo pathological zvinhu senge thrombotic zvirwere, zvirwere zvinotapukira, uye mamota anouraya.Zvinokurudzirwa kuti varwere vaende kudhipatimendi rechipatara rehematology kunorapwa nenguva.

1. Physiological zvinhu:
Panguva yekuzvitakura, mazinga ehomoni mumuviri achachinja, izvo zvinogona kukurudzira kuparara kwefibrin kuti ibudise D-dimer, iyo inogona kukonzera kuwedzera kweD-dimer muropa, asi kazhinji iri mukati meyakajairwa kana kuwedzera zvishoma. chinhu chakajairika chechimiro chemuviri uye kazhinji hachidi kurapwa kwakakosha.

2. Pathological zvinhu:
1. Thrombotic chirwere: Kana pane thrombotic chirwere mumuviri, zvakadai deep vein thrombosis, pulmonary embolism, nezvimwewo, zvinogona kutungamirira kune abnormal kushanda kweropa, kuita kuti ropa rive mu hypercoagulable state, uye kukurudzira fibrinolytic system hyperactivity, zvichiita kuti D-dimerization Kuwedzera kwefibrin degradation zvigadzirwa zvakadai semuviri uye imwe fibrin, iyo inozoita kuti kuwedzerwa kweD-dimer muropa.Panguva ino, pasi pekutungamirirwa kwachiremba, recombinant streptokinase yejekiseni, urokinase yejekiseni uye mamwe madhiragi anogona kushandiswa pakurapa kudzivirira kuumbwa kwethrombus;

2. Zvirwere zvinotapukira: Kana pane chirwere chakakomba mumuviri, sepsis, pathogenic microorganisms muropa inowedzera nokukurumidza mumuviri, inopinda mumatishu uye nhengo dzemuviri wose, inoparadza microvascular system, uye inoita capillary thrombosis. mumuviri wose.Izvo zvinotungamira mukuparadzira intravascular coagulation mumuviri wese, kukurudzira kukwidziridzwa kwefibrinolytic basa mumuviri, uye kukonzera kuwedzera kweD-dimer muropa.Panguva ino, murwere anogona kushandisa anti-infective mishonga yakadai secefoperazone sodium uye sulbactam sodium kubaya majekiseni sekurairwa nachiremba.;

3. Zvirwere zvinokuvadza: Masero akashata emamota achabudisa chinhu cheprocoagulant, anokurudzira kuumbwa kwethrombus mumidziyo yeropa, uye obva aita fibrinolytic system, zvichiita kuti kuwedzera kweD-dimer muropa.Panguva ino, paclitaxel jekiseni, Chemotherapy nemajekiseni emishonga yakadai secisplatin.Panguva imwecheteyo, iwe unogonawo kuita kuvhiyiwa kuti ubvise bundu maererano nezano rechiremba, izvo zvinobatsira pakupora kwechirwere.