Kuchinja kwekupedzisira kweThrombus uye Migumisiro Pamuviri


Munyori: Mutsivi   

Mushure mekunge thrombosis yaumbwa, chimiro chayo chinoshanduka pasi pechiito che fibrinolytic system uye kuyerera kweropa kuvhunduka uye kuvandudzwa kwemuviri.

Kune matatu makuru emhando dzekupedzisira shanduko mu thrombus:

1. Nyora, nyungudutsa, tora

Mushure mokunge thrombus yakaumbwa, fibrin mairi inotora yakawanda yeplasmin, kuitira kuti fibrin iri mu thrombus inova polypeptide inonyunguduka uye inonyunguduka, uye thrombus inonyorova.Panguva imwecheteyo, nokuti neutrophils mu thrombus inoparara uye inobudisa proteolytic enzymes, iyo thrombus inogonawo kunyungudutswa uye kupfava.

Iyo thrombus diki inonyungudika uye inonyungudika, uye inogona kunyudzwa zvachose kana kugezwa neropa pasina kusiya.

Chikamu chikuru chethrombus chakapfava uye chinodonha nyore nyore nekuyerera kweropa kuti ive embolus.Iyo emboli inovhara tsinga yeropa inoenderana nekuyerera kweropa, izvo zvinogona kukonzera embolism, nepo chikamu chasara chakarongeka.

2. Mechanization uye Recanalization

Hombe thrombi haisi nyore kunyungudika uye kunyura zvachose.Kazhinji, mukati memazuva maviri kusvika matatu mushure mekuumbwa kwe thrombus, granulation tissue inokura kubva kune yakakuvadzwa vascular intima apo thrombus yakabatanidzwa, uye zvishoma nezvishoma inotsiva thrombus, iyo inonzi thrombus sangano.
Kana iyo thrombus yakarongeka, iyo thrombus inoderera kana kunyungudika zvishoma, uye kutsemuka kunowanzo kuumbwa mukati meiyo thrombus kana pakati peiyo thrombus nemudziyo wemadziro, uye pamusoro inofukidzwa nekuwedzera vascular endothelial masero, uye pakupedzisira imwe kana akati wandei tsinga dzeropa. iyo inotaurirana neyokutanga yeropa tsinga inoumbwa.Recanalization yekuyerera kweropa kunonzi recanalization ye thrombus.

3. Calcification

Nhamba shoma yethrombi isingagoni kunyungudutswa zvachose kana kurongeka inogona kuderedzwa uye kuverengerwa nekarusiyamu munyu, kuumba matombo akaomarara aripo mumidziyo yeropa, anonzi phleboliths kana arterioliths.

Mhedzisiro yekugwamba kweropa pamuviri
Thrombosis ine maitiro maviri pamuviri.

1. Pamusoro pekuwedzera
Thrombosis inoumbwa pamudziyo weropa wakaputika, une hemostatic effect;thrombosis yemidziyo midiki yeropa yakatenderedza iyo inoputika foci inogona kudzivirira kupararira kwemabhakitiriya epathogenic uye chepfu.

2. Pazasi
Kuumbwa kwe thrombus mumudziyo weropa kunogona kuvhara mutsinga weropa, zvichiita kuti tishu uye nhengo ischemia uye infarction;
Thrombosis inoitika pavhavha yemwoyo.Pamusana pekurongeka kwethrombus, valve inova hypertrophic, shrunken, yakanamatira, uye yakaomeswa, zvichiita kuti valvular mwoyo chirwere uye kukanganisa mwoyo basa;
Iyo thrombus iri nyore kudonha uye kuumba embolus, iyo inomhanya nekuyerera kweropa uye inoumba embolism mune zvimwe zvikamu, zvichiita kuti infarction yakakura;
Massive microthrombosis mu microcirculation inogona kukonzera yakakura systemic hemorrhage uye kuvhunduka.